Genomics Facility

Partnering in complete Next-Gen Sequencing Solutions From Design to Sequencing to Analysis

We provide expert guidance on experiment design and approach with a diverse set of technologies to advance your project at any stage of development. Our mission is to get you the best genomic data and analysis to help move your research and pre-clinical projects forward. Contact our experienced team to plan solutions for your project and research goals.


For details on our Next-Gen Sequencing (NGS) services:
303.270.2650  |

Genomics Workflow


Integrated Team – Lab & Data Analysis

Our team of Laboratory and Data scientists have been pioneering translational genomics studies since the dawn of NGS. We specialize in working with sample sources that are difficult to sequence such as Low-Yield and FFPE, having optimized these techniques in-house over the past 10 years. Numerous grants have been obtained and supported through our diverse expertise in both research and clinical environments.



Evaluate an entire range of genomic activity to unlock your research and move to actionable targets. With expertise using multiple NGS platforms, including Thermo, Illumina and 10X Genomics, we match the right technology and experiment design to your needs.

  • RNA-Seq (Transcriptome)
  • Whole-genome Sequencing (WGS)
  • Whole-Exome Sequencing (WES)
  • Single Cell Genomics | CITE-Seq
  • Epigenetics
  • Chip-Seq | ATAC-Seq
  • <100pg Low-yield RNA
  • FFPE sample sequencing (DNA and RNA)
  • RNA/DNA Targeted Panel Sequencing


Next-Gen Sequencing Specialties

Our team has extensive research expertise in multiple fields to assist in study design and analysis.  We also specialize in low DNA/RNA content samples and difficult to analyze samples.

Data & Bioanalytics:

  • Network and Pathway Analysis
  • Longitudinal Analysis
  • Differential Expression Analysis
  • Variant Calling
  • Alternative Splicing Analysis
  • Inclusion/Exclusion Criteria Development

Customized Lab Techniques:

  • DNA Low-yield & FFPE (<1ng)
  • RNA Low-yield & FFPE (<100pg)
  • Custom DNA/RNA Panel Design
  • Infectious Disease / Pathogen Panels
  • ChIP-Seq
  • ATAC-Seq
  • CITE-Seq
  • MetaGenomics

BioMarkers and Pre-Clinical:

  • Biomarker Discovery
  • Biomarker Assessment
  • Pre-Clinical Research
  • Research Clinical Trials
  • Prospective Clinical Discovery
  • Retrospective Studies


Specialty Areas & Patient Groups

Our Center operates inside the #1 rated Pulmonary Medical Center in the US and can provide existing expertise across pulmonary, immunology and infectious disease research. Other fields are also widely supported with multiple resources and expertise.

  • Asthma
  • Cystic Fibrosis
  • Lung Cancers
  • Pulmonary Fibrosis / IPF
  • Tuberculosis / NTM
  • Immunology Disorders
  • Regenerative Medicine
  • Sarcoidosis
  • Hypersensitivity Pneumonitis (HP)


Equipment & Technologies

The Genomics Facility is unique in that we are agnostic about sequencing platforms, for example we run Illumina, Thermo, 10X Genomics and Wafergen NGS Platforms. This enables using the best available technology to best match the project and questions being investigated. Learn more

Sequencers and Genomic Platforms:

  • Illumina HiSeq 2500
  • Illumina MiSeq
  • Thermo Ion S5 XL (Qty2)
  • Thermo Ion PGM
  • 10X Genomics Single Cell Platform
  • Wafergen Single Cell Platform

Supporting Instruments:

  • Illumia cBot2
  • Thermo Ion Chef (Qty3)
  • Covaris S2 (Qty2)

About Us

We are a full service, integrated Genomics Facility housed within the Center for Genes, Environment and Health, which includes over 50 faculty and staff supporting research and clinical activities across a wide spectrum of fields. The Genomics Facility provides Next-Gen Sequencing services from expert planning through data analysis including RNA-Seq, Whole Exome Sequencing, Single-Cell sequencing and customized panels. Analysis results provided are meaningfully applied to the biology in question. The data is stored onsite and is ready for future data mining by our team or others when needed. Our team is trained to utilize both Illumina and Thermo Ion Sequencing Platforms, including many other technologies, to provide the best mix of capabilities for your genomics needs.

Kendra Walton
Genomics Manager, Genomics Facility
Center for Genes, Environment and Health

Brian O'Connor, PhD
Assoc. Professor, Director, Genomics Facility
Center for Genes, Environment and Health

Tasha Fingerlin, PhD
Professor, Director
Center for Genes, Environment and Health

Roland Marcus
Business Development, Partnerships
Center for Genes, Environment and Health


Contact Us Today