Featured: T-Cell Receptor Sequencing
Full data sets provided, custom reports generated and access to interactive data analysis tools to work with your data in ThermoFisher’s powerful Ion Reporter Cloud. Standard and Deep Sequencing options are available. Assistance with experiment design, sample preparation, study design and custom analysis from our data science group is available. Learn More
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Partnering in complete Next-Gen Sequencing Solutions From Design to Sequencing to Analysis
We provide expert guidance on experiment design and approach with a diverse set of technologies to advance your project at any stage of development. Our mission is to get you the best genomic data and analysis to help move your research and pre-clinical projects forward. Contact our experienced team to plan solutions for your project and research goals.
For details on our Next-Gen Sequencing (NGS) services:
303.270.2650 | Genomics@NJHealth.org
Discover more about the Genomics Facility
Integrated Team – Lab & Data Analysis
Our team of Laboratory and Data scientists have been pioneering translational genomics studies since the dawn of NGS. We specialize in working with sample sources that are difficult to sequence such as Low-Yield and FFPE, having optimized these techniques in-house over the past 10 years. Numerous grants have been obtained and supported through our diverse expertise in both research and clinical environments.
Evaluate an entire range of genomic activity to unlock your research and move to actionable targets. With expertise using multiple NGS platforms, including Thermo, Illumina and 10X Genomics, we match the right technology and experiment design to your needs.
Next-Gen Sequencing Specialties
Our team has extensive research expertise in multiple fields to assist in study design and analysis. We also specialize in low DNA/RNA content samples and difficult to analyze samples.
Data & Bioanalytics:
- Network and Pathway Analysis
- Longitudinal Analysis
- Differential Expression Analysis
- Variant Calling
- Alternative Splicing Analysis
- Inclusion/Exclusion Criteria Development
Customized Lab Techniques:
- DNA Low-yield & FFPE (<1ng)
- RNA Low-yield & FFPE (<100pg)
- Custom DNA/RNA Panel Design
- Infectious Disease / Pathogen Panels
BioMarkers and Pre-Clinical:
- Biomarker Discovery
- Biomarker Assessment
- Pre-Clinical Research
- Research Clinical Trials
- Prospective Clinical Discovery
- Retrospective Studies
Specialty Areas & Patient Groups
Our Center operates inside the #1 rated Pulmonary Medical Center in the US and can provide existing expertise across pulmonary, immunology and infectious disease research. Other fields are also widely supported with multiple resources and expertise.
- COPD / AATD
- Cystic Fibrosis
- Lung Cancers
- Pulmonary Fibrosis / IPF
- Tuberculosis / NTM
- Immunology Disorders
- Regenerative Medicine
- Hypersensitivity Pneumonitis (HP)
Equipment & Technologies
The Genomics Facility is unique in that we are agnostic about sequencing platforms, for example we run Illumina, Thermo, and 10X Genomics NGS Platforms. This enables using the best available technology to best match the project and questions being investigated. Learn more
Sequencers and Genomic Platforms:
- Thermo Ion S5 Prime
- Thermo Ion S5 XL
- Illumina MiSeq
- 10X Genomics Single Cell Chromium IX
- Thermo Ion Chef (Qty2)
- Covaris S2 (Qty2)
Partnership & Collaboration Opportunities
Partnerships and collaborations in all areas of NextGen Sequencing with Bioinformatics and Biostatistics support are available. Collaborations can leverage NJH’s unique patient populations in Respiratory and Immune Disorders and include scientific and medical expertise. Our experts specialize in include Asthma, COPD, Cystic Fibrosis, Pulmonary Fibrosis and iPF, Sarcoidosis, Tuberculosis (TB), Nontuberculosis (NTM) and various immune disorders.
We are a full service, integrated Genomics Facility housed within the Center for Genes, Environment and Health, which includes over 50 faculty and staff supporting research and clinical activities across a wide spectrum of fields. The Genomics Facility provides Next-Gen Sequencing services from expert planning through data analysis including RNA-Seq, Whole Exome Sequencing, Single-Cell sequencing and customized panels. Analysis results provided are meaningfully applied to the biology in question. The data is stored onsite and is ready for future data mining by our team or others when needed. Our team is trained to utilize both Illumina and Thermo Ion Sequencing Platforms, including many other technologies, to provide the best mix of capabilities for your genomics needs.
Trey Farmer, PhD
Tasha Fingerlin, PhD