Clinical Trials Search

Our researchers are currently in need of adult and pediatric study participants to help us pursue better treatments and cures. Participants may receive medical evaluations and procedures, study medication, disease-related education and possible financial compensation for time, travel and participation.

 

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Compensation


Can Interactive Technology Improve Brain Function in Lupus Patients?

People with systemic lupus erythematosus (SLE) may be able to improve brain function with Project EVO, an interactive digital technology currently in development with Akili Interactive. Learn more.

  • Gender: Any Gender
  • Ages: 18-65
  • Compensation: Provided
  • Time Required: 1 interview, 2 appointments, ~30 minutes of video play over 4 weeks

Immune Pathways & Development of Sarcoidosis

If you are an adult with sarcoidosis who is not on immunosuppressive therapy, you may be able to help our researchers learn more about different types of sarcoidosis and how it develops.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: Up to 2 visits

Treating Insomnia & OSA with Cognitive Behavioral Therapy

Does your mind race at night when you're trying to sleep? Our researchers are studying how people with insomnia and obstructive sleep apnea can benefit from cognitive behavioral therapy, a goal-oriented type of treatment that aims to identify and change inaccurate or negative thinking patterns...

  • Gender: Any Gender
  • Ages: 21-80
  • Compensation: Provided
  • Time Required: 6-12 visits and 1 phone call totaling 11.5-17.5 hours over 12 months.

Can Investigational Medication Reduce Eczema Symptoms in Children?

Does your child have mild-to-severe eczema? They may qualify for a clinical trial to see if an investigational medication can safely and effectively reduce their symptoms. Compensation is provided.

  • Gender: Any Gender
  • Ages: 6-11
  • Compensation: Provided
  • Time Required: 13 visits over seven months

Mineral Dust & Lung Disease

Our researchers are studying lung diseases that develop from inhaling mineral dust over time. Although the cause of diseases such as "black lung" are known, it is not well understood why some people develop these diseases and others don't.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Not Provided
  • Time Required: 45-min phone call, followed by 30-min phone calls.

Impact of Combination Therapy on Cystic Fibrosis (TEACH Study)

The purpose of this study is to determine how two medications, azithromycin and inhaled tobramycin, work when taken together to treat cystic fibrosis (CF) patients with chronic pseudomonas aeruginosa (PA) lung infections.

  • Gender: Any Gender
  • Ages: 12+
  • Compensation: Provided
  • Time Required: 3 visits over 6 weeks totaling up to 7 hours

Inhaled Investigational Medication for Cystic Fibrosis

The purpose of this study is to better understand how an investigational medication, QBW276, affects people with cystic fibrosis (CF).

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 1 month, 1 1/2 months or 4 months

Sleep Apnea & Quality of Life

Our researchers are studying how to help people use positive airway pressure (PAP) to treat their obstructive sleep apnea, a serious disorder that, if left untreated, can lead to high blood pressure, stroke, heart problems, diabetes and depression.

  • Gender: Any Gender
  • Ages: 21-80
  • Compensation: Provided
  • Time Required: 4 visits totaling about 4 hours over 12 months

New Medication for Uncontrolled Eczema

Are you one of the many people with atopic dermatitis (eczema) who continues to have dry, itchy skin, and repeat infections that are not controlled by your medicine? Our researchers are seeking participants for a clinical trial that will test a medication called dupilumab that was recently...

  • Gender: Any Gender
  • Ages: 18-65
  • Compensation: Provided
  • Time Required: 10 visits and 1 telephone call over about 6-7 months

Combination Therapy for Pediatric Asthma Patients

Our researchers are studying an investigational combination of medications, one used to treat asthma in adults and the other not yet approved to treat adult asthma, to determine if it can improve symptoms and lung function in asthma patients age 5 to 17.

  • Gender: Any Gender
  • Ages: 5-17
  • Compensation: Provided
  • Time Required: 7 visits up to 29 weeks

Preventing COPD Flare-ups with Beta Blockers

Chronic obstructive pulmonary disease (COPD) patients age 40-85 are needed for a clinical trial to see if a commonly prescribed heart medication can reduce COPD flare-ups.

  • Gender: Any Gender
  • Ages: 40-85
  • Compensation: Provided
  • Time Required: 10 visits & 10 phone visits over 1 year

Teens Age 12-17 with Asthma

Our researchers are studying an investigational medication to determine if it improves lung function in teens with asthma. By blocking a key receptor that causes inflammation in the lungs, the medication may improve and prevent symptoms such as wheezing and shortness of breath.

  • Gender: Any Gender
  • Ages: 12-17
  • Compensation: Provided
  • Time Required: About 9 visits over approximately 19 weeks

New Antibody Targets Severe Asthma

Is your asthma poorly controlled despite using inhalers? Our researchers are studying an investigational medicine that targets a substance known to play a role in causing asthma. You may be able to help them determine if this medication is effective in treating severe asthma.

  • Gender: Any Gender
  • Ages: 18-80
  • Compensation: Provided
  • Time Required: 19 visits over 69-71 weeks

Using Tele-coaching to Manage Cystic Fibrosis

Our researchers are studying how tele-coaching can be used to help people with cystic fibrosis (CF) manage their treatment plan, which often includes many medications and airway-clearance routines. Tele-coaching includes a telephone interview and web conferencing.

  • Gender: Any Gender
  • Ages: 18-25
  • Compensation: Provided
  • Time Required: Up to 9 months

Investigational Drug Targets Cystic Fibrosis Mutation and Regulator

Our researchers are studying glycerol phenylbutyrate (GPBA), also known as RAVICTI®, to determine how safe it is and how well people tolerate it in the treatment of cystic fibrosis (CF).

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 5 visits totalling up to 21 hours

Combination Therapy for Poorly Controlled Asthma

Are you an adult with poorly controlled moderate to severe asthma? Our researchers want to find out if adding an investigational medication to an existing therapy is effective in treating asthma

  • Gender: Any Gender
  • Ages: 18-75
  • Compensation: Provided
  • Time Required: 7 1/2 months

Medication Targets Underlying Mechanism of Cystic Fibrosis

The purpose of this study is to test the effectiveness of a new investigational medication, PTI-801, in treating cystic fibrosis (CF).

  • Gender: Any Gender
  • Ages: 18-55
  • Compensation: Provided
  • Time Required: Up to 8 visits totaling up to 35 hours

OPUS Registry for Patients Using Opsumit®

The purpose of this study is to learn more about how Opsumit® (the commercial form of the medication macitentan) is used in clinical practice to treat pulmonary arterial hypertension (PAH) and other conditions.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 1 year

Investigational Medication for COPD Lung Damage

Adults age 40 or older are needed to help our researchers determine if an investigational medication can help slow damage to the lungs in people who have COPD with emphysema.

  • Gender: Any Gender
  • Ages: 40+
  • Compensation: Provided
  • Time Required: 7 visits, approximately 19 hours

Investigational Medication for AATD & COPD

Do you have alpha-1 with emphysema? Our researchers want to learn if an investigational medication, a hyaluronic acid inhalation solution, can be used to treat adults who have alpha-1 antitrypsin deficiency (AATD) with emphysema.

  • Gender: Any Gender
  • Ages: 18-80
  • Compensation: Provided
  • Time Required: 5 visits

Investigational Medication Sirolimus for Lymphangioleiomyomatosis (LAM)

The purpose of this study is to see if a drug called sirolimus slows development of lymphangioleiomyomatosis (LAM), a lung disease in which abnormal cells growing inside the lungs prevent them from working properly.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 2 years

Early-Stage Lung Cancer Surgery vs. Radiation Therapy Comparison

The purpose of this study is to gather information about treatment of early-stage lung cancer in order to compare the effectiveness of surgery versus radiation therapy, potentially improving outcomes for patients with early-stage lung cancer.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 4 hours, 45 mins.

Can Investigational Drug Benefit Lung Cancer Surgery Patients?

The purpose of this clinical trial is to see if it better to receive an investigational medication or no further treatment after surgery (and possibly chemotherapy) to remove non-small cell lung cancer (NSCLC).

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Not Provided
  • Time Required: Up to 12 months

Can Investigational Medication Benefit FHP Patients?

The purpose of this clinical trial is to study the safety and potential benefits of treating fibrotic hypersensitivity pneumonitis (FHP) with an investigational medication.

  • Gender: Any Gender
  • Ages: 18-80
  • Compensation: Provided
  • Time Required: 8 visits and 6 phone calls totaling about 12 hours of participation over 13 months

Pulmonary Hypertension & Lung Disease

Do you have pulmonary hypertension (PH) related to lung disease? You may qualify for a clinical trial to help researchers determine the safety and effectiveness of an investigational medication.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 7 visits over 20 weeks

Severe Asthma Investigational Medication

Is your asthma poorly controlled despite consistent use of an inhaler and other medication? You may qualify for a clinical trial to see if an investigational drug helps people with severe asthma.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 11 visits over 60 weeks

Steroid-Resistant Asthma Medication Study

If you are age 18 to 65 with asthma not improved by inhaled steroids, you may be eligible to participate in a clinical trial and try a new investigational medication.

  • Gender: Any Gender
  • Ages: 18-65
  • Compensation: Provided
  • Time Required: 2 visits over 7-8 days

Current & Former Smokers Needed for Lung Research Study

Our researchers are studying the lungs of current and former smokers to understand how to improve the diagnosis and treatment of Chronic Obstructive Pulmonary Disease (COPD), a disease that is common among smokers. You do not need to have COPD to participate in this study.

  • Gender: Any Gender
  • Ages: 55-77
  • Compensation: Provided
  • Time Required: 1-2 hour visit (can be scheduled immediately after your CT if there is space available)

Long-Term Medical Effects of Marijuana Use

What are the positive and negative long-term medical effects of marijuana use? You can help our researchers find out if you live in Colorado, are age 21 to 80 and use marijuana regularly.

  • Gender: Any Gender
  • Ages: 21-80
  • Compensation: Provided
  • Time Required: 1 to 2 visits (3.5 hours long)

Genetic Risk for Sarcoidosis

Our researchers are looking for people with and without sarcoidosis for a clinical trial on genetic markers associated with the disease.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 1 visit

|< <  1 2   > >|

Can Interactive Technology Improve Brain Function in Lupus Patients?

People with systemic lupus erythematosus (SLE) may be able to improve brain function with Project EVO, an interactive digital technology currently in development with Akili Interactive. Learn more.

  • Gender: Any Gender
  • Ages: 18-65
  • Compensation: Provided
  • Time Required: 1 interview, 2 appointments, ~30 minutes of video play over 4 weeks

Immune Pathways & Development of Sarcoidosis

If you are an adult with sarcoidosis who is not on immunosuppressive therapy, you may be able to help our researchers learn more about different types of sarcoidosis and how it develops.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: Up to 2 visits

Treating Insomnia & OSA with Cognitive Behavioral Therapy

Does your mind race at night when you're trying to sleep? Our researchers are studying how people with insomnia and obstructive sleep apnea can benefit from cognitive behavioral therapy, a goal-oriented type of treatment that aims to identify and change inaccurate or negative thinking patterns...

  • Gender: Any Gender
  • Ages: 21-80
  • Compensation: Provided
  • Time Required: 6-12 visits and 1 phone call totaling 11.5-17.5 hours over 12 months.

Mineral Dust & Lung Disease

Our researchers are studying lung diseases that develop from inhaling mineral dust over time. Although the cause of diseases such as "black lung" are known, it is not well understood why some people develop these diseases and others don't.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Not Provided
  • Time Required: 45-min phone call, followed by 30-min phone calls.

Impact of Combination Therapy on Cystic Fibrosis (TEACH Study)

The purpose of this study is to determine how two medications, azithromycin and inhaled tobramycin, work when taken together to treat cystic fibrosis (CF) patients with chronic pseudomonas aeruginosa (PA) lung infections.

  • Gender: Any Gender
  • Ages: 12+
  • Compensation: Provided
  • Time Required: 3 visits over 6 weeks totaling up to 7 hours

Inhaled Investigational Medication for Cystic Fibrosis

The purpose of this study is to better understand how an investigational medication, QBW276, affects people with cystic fibrosis (CF).

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 1 month, 1 1/2 months or 4 months

Sleep Apnea & Quality of Life

Our researchers are studying how to help people use positive airway pressure (PAP) to treat their obstructive sleep apnea, a serious disorder that, if left untreated, can lead to high blood pressure, stroke, heart problems, diabetes and depression.

  • Gender: Any Gender
  • Ages: 21-80
  • Compensation: Provided
  • Time Required: 4 visits totaling about 4 hours over 12 months

New Medication for Uncontrolled Eczema

Are you one of the many people with atopic dermatitis (eczema) who continues to have dry, itchy skin, and repeat infections that are not controlled by your medicine? Our researchers are seeking participants for a clinical trial that will test a medication called dupilumab that was recently...

  • Gender: Any Gender
  • Ages: 18-65
  • Compensation: Provided
  • Time Required: 10 visits and 1 telephone call over about 6-7 months

Preventing COPD Flare-ups with Beta Blockers

Chronic obstructive pulmonary disease (COPD) patients age 40-85 are needed for a clinical trial to see if a commonly prescribed heart medication can reduce COPD flare-ups.

  • Gender: Any Gender
  • Ages: 40-85
  • Compensation: Provided
  • Time Required: 10 visits & 10 phone visits over 1 year

New Antibody Targets Severe Asthma

Is your asthma poorly controlled despite using inhalers? Our researchers are studying an investigational medicine that targets a substance known to play a role in causing asthma. You may be able to help them determine if this medication is effective in treating severe asthma.

  • Gender: Any Gender
  • Ages: 18-80
  • Compensation: Provided
  • Time Required: 19 visits over 69-71 weeks

Using Tele-coaching to Manage Cystic Fibrosis

Our researchers are studying how tele-coaching can be used to help people with cystic fibrosis (CF) manage their treatment plan, which often includes many medications and airway-clearance routines. Tele-coaching includes a telephone interview and web conferencing.

  • Gender: Any Gender
  • Ages: 18-25
  • Compensation: Provided
  • Time Required: Up to 9 months

Investigational Drug Targets Cystic Fibrosis Mutation and Regulator

Our researchers are studying glycerol phenylbutyrate (GPBA), also known as RAVICTI®, to determine how safe it is and how well people tolerate it in the treatment of cystic fibrosis (CF).

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 5 visits totalling up to 21 hours

Combination Therapy for Poorly Controlled Asthma

Are you an adult with poorly controlled moderate to severe asthma? Our researchers want to find out if adding an investigational medication to an existing therapy is effective in treating asthma

  • Gender: Any Gender
  • Ages: 18-75
  • Compensation: Provided
  • Time Required: 7 1/2 months

Medication Targets Underlying Mechanism of Cystic Fibrosis

The purpose of this study is to test the effectiveness of a new investigational medication, PTI-801, in treating cystic fibrosis (CF).

  • Gender: Any Gender
  • Ages: 18-55
  • Compensation: Provided
  • Time Required: Up to 8 visits totaling up to 35 hours

OPUS Registry for Patients Using Opsumit®

The purpose of this study is to learn more about how Opsumit® (the commercial form of the medication macitentan) is used in clinical practice to treat pulmonary arterial hypertension (PAH) and other conditions.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 1 year

Investigational Medication for COPD Lung Damage

Adults age 40 or older are needed to help our researchers determine if an investigational medication can help slow damage to the lungs in people who have COPD with emphysema.

  • Gender: Any Gender
  • Ages: 40+
  • Compensation: Provided
  • Time Required: 7 visits, approximately 19 hours

Investigational Medication for AATD & COPD

Do you have alpha-1 with emphysema? Our researchers want to learn if an investigational medication, a hyaluronic acid inhalation solution, can be used to treat adults who have alpha-1 antitrypsin deficiency (AATD) with emphysema.

  • Gender: Any Gender
  • Ages: 18-80
  • Compensation: Provided
  • Time Required: 5 visits

Investigational Medication Sirolimus for Lymphangioleiomyomatosis (LAM)

The purpose of this study is to see if a drug called sirolimus slows development of lymphangioleiomyomatosis (LAM), a lung disease in which abnormal cells growing inside the lungs prevent them from working properly.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 2 years

Early-Stage Lung Cancer Surgery vs. Radiation Therapy Comparison

The purpose of this study is to gather information about treatment of early-stage lung cancer in order to compare the effectiveness of surgery versus radiation therapy, potentially improving outcomes for patients with early-stage lung cancer.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 4 hours, 45 mins.

Can Investigational Drug Benefit Lung Cancer Surgery Patients?

The purpose of this clinical trial is to see if it better to receive an investigational medication or no further treatment after surgery (and possibly chemotherapy) to remove non-small cell lung cancer (NSCLC).

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Not Provided
  • Time Required: Up to 12 months

Can Investigational Medication Benefit FHP Patients?

The purpose of this clinical trial is to study the safety and potential benefits of treating fibrotic hypersensitivity pneumonitis (FHP) with an investigational medication.

  • Gender: Any Gender
  • Ages: 18-80
  • Compensation: Provided
  • Time Required: 8 visits and 6 phone calls totaling about 12 hours of participation over 13 months

Pulmonary Hypertension & Lung Disease

Do you have pulmonary hypertension (PH) related to lung disease? You may qualify for a clinical trial to help researchers determine the safety and effectiveness of an investigational medication.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 7 visits over 20 weeks

Severe Asthma Investigational Medication

Is your asthma poorly controlled despite consistent use of an inhaler and other medication? You may qualify for a clinical trial to see if an investigational drug helps people with severe asthma.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 11 visits over 60 weeks

Steroid-Resistant Asthma Medication Study

If you are age 18 to 65 with asthma not improved by inhaled steroids, you may be eligible to participate in a clinical trial and try a new investigational medication.

  • Gender: Any Gender
  • Ages: 18-65
  • Compensation: Provided
  • Time Required: 2 visits over 7-8 days

Current & Former Smokers Needed for Lung Research Study

Our researchers are studying the lungs of current and former smokers to understand how to improve the diagnosis and treatment of Chronic Obstructive Pulmonary Disease (COPD), a disease that is common among smokers. You do not need to have COPD to participate in this study.

  • Gender: Any Gender
  • Ages: 55-77
  • Compensation: Provided
  • Time Required: 1-2 hour visit (can be scheduled immediately after your CT if there is space available)

Long-Term Medical Effects of Marijuana Use

What are the positive and negative long-term medical effects of marijuana use? You can help our researchers find out if you live in Colorado, are age 21 to 80 and use marijuana regularly.

  • Gender: Any Gender
  • Ages: 21-80
  • Compensation: Provided
  • Time Required: 1 to 2 visits (3.5 hours long)

Genetic Risk for Sarcoidosis

Our researchers are looking for people with and without sarcoidosis for a clinical trial on genetic markers associated with the disease.

  • Gender: Any Gender
  • Ages: 18+
  • Compensation: Provided
  • Time Required: 1 visit

Psoriasis & Inflammation

How does inflammation differ in psoriasis and atopic dermatitis (eczema) patients? Our researchers are trying to find out. If you or your child (age 12 or older) has a history of psoriasis, we need your help for a clinical trial.

  • Gender: Any Gender
  • Ages: Not Specified
  • Compensation: Provided
  • Time Required: 1 to 2 visits

Pulmonary Fibrosis & Genetic Factors

The purpose of this study is to investigate inherited genetic factors that play a role in the development of familial pulmonary fibrosis and to identify a group of genes that predispose individuals to develop pulmonary fibrosis.

  • Gender: Any Gender
  • Ages: Not Specified
  • Compensation: Not Provided
  • Time Required: Not Specified

Can Better Sleep Prevent COPD Hospital Visits?

The purpose of this study is to prevent patients who are hospitalized with COPD from having to return to the hospital because of their disease.

  • Gender: Any Gender
  • Ages: 40+
  • Compensation: Provided
  • Time Required: 60 days, unless participants choose to enroll in the registry for the three-year follow-up.

|< <  1 2   > >|

Can Investigational Medication Reduce Eczema Symptoms in Children?

Does your child have mild-to-severe eczema? They may qualify for a clinical trial to see if an investigational medication can safely and effectively reduce their symptoms. Compensation is provided.

  • Gender: Any Gender
  • Ages: 6-11
  • Compensation: Provided
  • Time Required: 13 visits over seven months

Combination Therapy for Pediatric Asthma Patients

Our researchers are studying an investigational combination of medications, one used to treat asthma in adults and the other not yet approved to treat adult asthma, to determine if it can improve symptoms and lung function in asthma patients age 5 to 17.

  • Gender: Any Gender
  • Ages: 5-17
  • Compensation: Provided
  • Time Required: 7 visits up to 29 weeks

Teens Age 12-17 with Asthma

Our researchers are studying an investigational medication to determine if it improves lung function in teens with asthma. By blocking a key receptor that causes inflammation in the lungs, the medication may improve and prevent symptoms such as wheezing and shortness of breath.

  • Gender: Any Gender
  • Ages: 12-17
  • Compensation: Provided
  • Time Required: About 9 visits over approximately 19 weeks

Atopic Dermatitis (Eczema) & Skin-Infection Risk

If you or your child age 3 or older has atopic dermatitis (eczema), you may be able to help our researchers learn why some people with eczema have increased risk of skin infection.

  • Gender: Any Gender
  • Ages: 3-80
  • Compensation: Provided
  • Time Required: 1 or more visits

Fighting Atopic Dermatitis (Eczema) Skin Infections

Do you have eczema? If you are age 18 to 60, you may qualify for an NIH sponsored clinical trial to see if an investigational lotion is safe and if the lotion reduces or even eliminates, bacteria that cause skin infections. Compensation provided for qualified participants.

  • Gender: Any Gender
  • Ages: 18-60
  • Compensation: Provided
  • Time Required: 38 days (7-8 in-person visits, 2-3 telephone visits)

Link Between Eczema & Food Allergies in Newborns

Are you pregnant? Do you have a family history of allergic disease (asthma, eczema, environmental allergies, hay fever, etc.)? You may be able to help our researchers determine if your child and others are at risk of developing eczema and food allergies.

  • Gender: Any Gender
  • Ages: Parents 18-50, newborns 3-6 months
  • Compensation: Not Provided
  • Time Required: Four 1-hour visits over 6 months

Potential Reduction of Cystic Fibrosis Pulmonary Flare-Ups

The purpose of this research study is to determine if an investigational medication can reduce inflammation, tissue scarring, and the number of pulmonary exacerbations, or episodes when breathing is more difficult, in people with cystic fibrosis (CF).

  • Gender: Any Gender
  • Ages: 12+
  • Compensation: Provided
  • Time Required: 9 visits (15 hours over about 32 weeks)