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Treating Deployment-Related Asthma with Supplements

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Trial Objectives


Many people returning from military deployment have developed asthma as a result of inhaling hazardous materials. Exposures to diesel, burn pits, biomass smoke and sandstorms during deployment likely play a role. Some people with deployment-related asthma do not respond well to standard asthma medications.

In this study, researchers are investigating whether a supplement called L-citrulline will help improve asthma symptoms and lung function for veterans with deployment-related asthma. Over several weeks, participants will be provided with L-citrulline supplements and a placebo powder (without knowing which they are taking first) and tested to see if there is any change in lung function.

Who Can Participate


Adults diagnosed with deployment-related asthma who have a smoking history of 15 pack years or less and who haven’t smoked in the last three months are eligible. Participants may not be pregnant, breastfeeding or planning on getting pregnant within six months.

Age: 18-70 Gender Any

Estimated Time Commitment


5-6 clinic visits over 18-22 weeks

Payment & Reimbursement


Payment Provided

Travel Reimbursement Not Available

Trial Contact


For more information, contact:

Michelle Kramaric
303.270.2634

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Trial Location


National Jewish Main Campus, Denver, CO

Trial Sponsors


Department of Defense

Principal Investigators

Cecile S. Rose

Cecile S. Rose, MD, MPH

Co-Investigators

Silpa D. Krefft

Silpa D. Krefft, MD, MPH

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