Pulmonary Arterial Hypertension & increased dose of Opsumit Request More Information Trial Objective The UNISUS study will compare the effectiveness and safety of a higher dose of an investigational medication called Opsumit to a lower dose in people with pulmonary arterial hypertension (PAH). The results of the UNISUS Study will provide more information about the investigational medication’s effectiveness and safety when it is given as a higher dose to adults with PAH. Participants will be randomly assigned to receive a tablet of 10 mg or 75 mg dose of Opsumit to take once a day. During clinic visits, participants may have their vital signs taken, provide a blood sample and perform a walking test. Enrollment Active Clinical Trials Currently Recruiting Who Can Participate Patients diagnosed with pulmonary arterial hypertension Age: 18+ Gender: Any Gender Estimated Time Commitment Up to 4 years. Year 1: monthly visits. Year 2: visits every three months. Years 3-4: visits every six months. × Payments are intended to compensate the participant for their time and effort during the study. Payments are typically given to the participant at the end of each completed study visit. Reimbursements are intended to compensate the participant for travel-related expenses. They must be approved by the study staff and require you to turn in receipts. Travel reimbursement will vary from study to study. Payment & Reimbursement Payment: Provided Travel Reimbursement: Available Trial Contact For more information, contact: Jennifer Underwood 303.398.1518 Request More Information Trial Location National Jewish Main Campus, Denver, CO Trial Sponsors Janssen Pharmaceuticals Principal Investigators Mohammad Dalabih, MD + × Mohammad Dalabih, MD Assistant Professor Division of Pulmonary, Critical Care & Sleep Medicine Department of Medicine View Full Profile Make an Appoinment Co-Investigators Marjorie Patricia George, MD + × Marjorie Patricia George, MD Associate Professor Director, Pulmonary Hypertension Program Division of Pulmonary, Critical Care & Sleep Medicine Department of Medicine View Full Profile Make an Appoinment Vera Pillitteri, DNP, FNP-BC + × Vera Pillitteri, DNP, FNP-BC Family Nurse Practitioner Division of Cardiology Department of Medicine View Full Profile Patient Rating 4.9 out of 5 stars Make an Appoinment Request More Information By completing this form, you agree to learn more about this study and see if you qualify. First Name:* Last Name:* Email Address:* Phone:* I would also like to receive periodic emails with health information, news and clinical research updates from National Jewish Health: YesNo
Trial Objective The UNISUS study will compare the effectiveness and safety of a higher dose of an investigational medication called Opsumit to a lower dose in people with pulmonary arterial hypertension (PAH). The results of the UNISUS Study will provide more information about the investigational medication’s effectiveness and safety when it is given as a higher dose to adults with PAH. Participants will be randomly assigned to receive a tablet of 10 mg or 75 mg dose of Opsumit to take once a day. During clinic visits, participants may have their vital signs taken, provide a blood sample and perform a walking test.