William J. Janssen, MD Make an Appointment Ask a Question Refer Patient William J. Janssen, MD, is a pulmonologist at National Jewish Health. Dr. Janssen serves as the Section Head of Critical Care Medicine. Section Head, Critical Care Medicine Professor of Medicine Section of Critical Care Medicine Division of Pulmonary, Critical Care & Sleep Medicine Department of Medicine 5280 Top Doctors 2022 Previously a 5280 Top Doctor America’s Top Doctors 2015 — Castle Connolly, Medical, Ltd. Recognized in America’s Top Doctors — Castle Connolly, Inc. Best Doctors in America® 2019-2020 — Best Doctors, Inc. Recognized in Best Doctors in America® — Best Doctors, Inc. America’s Top Doctors 2020 — Castle Connolly Medical, Ltd. Email Profile Print Profile Overview Contact Info & Locations Patient Ratings & Comments Programs & Services COPD Program Department of Medicine Division of Pulmonary, Critical Care and Sleep Medicine (Adult) Rose Medical Center Critical Care Service Section of Critical Care Medicine Swedish Medical Center Critical Care Service Specialties & Conditions Chronic Obstructive Pulmonary Disease (COPD) Research Areas Cellular and Molecular Biology Inflammation Pulmonary Disease Research, Other Chronic Obstructive Pulmonary Disease (COPD) Special Interests Clinical Interests My clinical interests are in critical care medicine and chronic obstructive pulmonary disease. I also specialize in the treatment of septic shock, acute lung injury, and ARDS (acute respiratory distress syndrome). Research Interests My research is focused on mechanisms of repair following acute and chronic lung injury. This includes studying how lung collectins influence alveolar macrophage phenotype, function, and fate in healthy lungs and during inflammation. I am also interested in the role that bone-marrow-derived stem cells (including endothelial progenitor cells) play in recovery from lung injury. See More View Curriculum Vitae View Publications News & Videos National Jewish Health Awarded $11.5 Million in Department of Defense Grants Education Education 1994 - 1998 The Ohio State University, MD 1993 The Ohio State University, BS, Mechanical Engineering Residency 1998 - 2001 The Ohio State University, Internal Medicine Fellowship 2002 - 2005 University of Colorado Denver, Pulmonary and Critical Care Awards & Recognition 2014: Best Doctors in America, Best Doctors, Inc. Board Certification Internal Medicine, Pulmonary Medicine, Critical Care Professional Memberships American Thoracic Society Society of Critical Care Medicine American College of Chest Physicians Publications Sareli AE, Janssen WJ, Sterman D, Saint S, Pyeritz RF. What’s the connection? New Eng J. Med. 2008; 358(6):626-32. Ezzie E, Janssen WJ, O’Brien, JM, Fox C, Schwarz MI. Failure to respond, New Eng J Med. 2008; 358(1):70-4. Linderman DL, Janssen WJ. Critical care medicine for the hospitalist. Med Clin N. America 2008;92:467–479. Janssen WJ, McPhillips KA, Dickinson MG, Derek J. Linderman DJ, Morimoto K, Xiao YQ, Oldham KM, Vandivier RW,Henson PM, Gardai SJ.Surfactant Proteins A and D Tonically Suppress Alveolar Macrophage Phagocytosis via Interaction with SIRP?. Am J Respir Cell Crit Care Med. 2008;178)2):158-67 McPhillips K, Janssen WJ, Ghosh M, Byrne A, Gardai SJ, Remigio L, Bratton DL, Kang JL, Henson PM. TNFa inhibits macrophage clearance of apoptotic cells via cPLA2 and oxidant-dependent mechanisms. J Immunol. 2007;178(12):8117-2612. Hospital Affiliations Colorado Acute Long Term HospitalExempla Lutheran Medical CenterRose Medical CenterSky Ridge Medical CenterSt. Joseph Hospital - DenverSwedish Medical CenterUniversity of Colorado Hospital Academic Affiliations Assistant Professor of Medicine, University of Colorado Denver Conflicts of Interest National Jewish Health physicians and scientists may collaborate with pharmaceutical or other industries to develop medical and scientific breakthroughs or to provide education on trends in quality medical practice and outcomes to physicians and health professionals around the country. National Jewish Health maintains a strict conflict of interest policy to ensure that all potential conflicts are clearly visible and that management plans are put in place in order to further innovation and education while ensuring the protection of our patients and the integrity of our research. National Jewish Health publicly discloses any payment to our physicians or scientists. View this faculty member’s industry relationships and collaborations. Ask a Question through Patient Portal Sign in to your My National Jewish Health patient portal account to communicate with your care team, manage appointments, and more. Create an Account Contact Information Office: 877.225.5654 Locations National Jewish Health Main Campus 1400 Jackson St. Denver, CO 80206 Saint Joseph Hospital 1835 Franklin Street Denver, CO 80218 Patient Ratings The Patient Rating score is an average of all responses to care provider related questions on our independent rating system, the Press Ganey Patient Satisfaction Survey. This survey is about the patient care experience and does not address crucial characteristics like medical decision-making, prescribing the best therapy, and patient outcomes. Responses are measured on a scale of 1 to 5, with 5 being the best score. Learn more about our patient satisfaction survey. Comments Comments are collected in our Press Ganey Patient Satisfaction Surveys. Patients are de-identified to protect confidentiality and patient privacy. Learn more about our patient satisfaction survey.