Brian J. Day, PhD Ask a Question Refer Patient Brian J. Day, PhD, is a researcher at National Jewish Health. Dr. Day serves as the Vice Chair of Research in the Medicine Office of Research. Vice Chair of Research, Medicine Office of Research Professor Department of Medicine 5280 Top Doctors 2020 Previously a 5280 Top Doctor America’s Top Doctors 2015 — Castle Connolly, Medical, Ltd. Recognized in America’s Top Doctors — Castle Connolly, Inc. Best Doctors in America® 2019-2020 — Best Doctors, Inc. Recognized in Best Doctors in America® — Best Doctors, Inc. America’s Top Doctors 2020 — Castle Connolly Medical, Ltd. Email Profile Print Profile Overview Contact Info & Locations Research Areas Basic Immunology Cancer Chronic Beryllium Disease Cystic Fibrosis (CF) Environmental and Occupational Diseases Infectious Diseases Inflammation Oxidative Stress Chronic Obstructive Pulmonary Disease (COPD) Special Interests Research Interests Cystic Fibrosis, COPD, chronic beryllium disease, interstitial lung disease, sulfur mustard lung injury, drug development. Adaptive glutathione responses to cigarette smoke in COPD. (NIH RO1 HL084469-05) (Primary Investigator). Novel Antioxidant Therapeutics for Sulfur Mustard Toxicity. (NIH U54 ES015678-06) (Project 2 Leader). Modulation of lung inflammation by CFTR-dependent thiols. (Cystic Fibrosis Foundation Research Grant) (Primary Investigator). Targeting oxidative stress in chronic beryllium disease.(NIH RO1 ES017582-04) (Multiple Primary Investigator). News & Videos National Jewish Health Awarded $11.5 Million in Department of Defense Grants Education Education 1992 Purdue University (W Lafayette, IN), PhD, Pharmacology and Toxicology 1984 University of Montana (Missoula, MT), BS with Honors, School of Pharmacy Fellowship 1995 Duke University (Durham, NC), Post-doctoral Integrated Toxicology & Pulmonary Fellow Awards & Recognition Basic Sciences Section Head, Department of Medicine, National Jewish Health Chief Science Officer, Aeolus Pharmaceuticals Chairman, Board of Publications Committee, Mechanisms Specialty Section Councilor, Society of Toxicology NIH Study Section Member, LIRR Professional Memberships Society of Toxicology American Thoracic Society Society of Free Radical Biology and Medicine American Heart Association American Chemical Society Publications Dobis, D.R., Sawyer R.T., Gillespie M.M., Huang J., Newman L.S., Maier L.A. and Day B.J. Modulation of Lymphocyte Proliferation by Antioxidants in Chronic Beryllium Disease. Am. J. Respir. Crit. Care Med. 177:1002-1011, 2008. Day, B.J. Antioxidants as potential therapeutics for lung fibrosis. Antiox Redox Sig,10:355-370, 2008. Kachadourian, R and Day, B.J. Flavonoid-induced glutathione depletion: potential implications for cancer treatment. Free Radic. Biol. Med. 41:65-76, 2006. Velsor, L.W., Kariya C.,Kachadourian, R., and Day, B.J. Mitochondrial oxidative stress in the lungs of cystic fibrosis transmembrane conductance regulator protein mutant mice. Am. J. Respir. Cell Mol. Biol. 35:579-586, 2006. Day BJ, van Heeckeren AM, Min E, and Velsor L. Role for CFTR in a glutathione response to bronchopulmonary pseudomonas infection. Infect Immun 72:2045-2051, 2004. Academic Affiliations Professor of Medicine, Pharmaceutical Sciences and Immunology, University of Colorado Denver Professor, Colorado School of Public Health, University of Colorado Denver Conflicts of Interest National Jewish Health physicians and scientists may collaborate with pharmaceutical or other industries to develop medical and scientific breakthroughs or to provide education on trends in quality medical practice and outcomes to physicians and health professionals around the country. National Jewish Health maintains a strict conflict of interest policy to ensure that all potential conflicts are clearly visible and that management plans are put in place in order to further innovation and education while ensuring the protection of our patients and the integrity of our research. National Jewish Health publicly discloses any payment to our physicians or scientists. View this faculty member’s industry relationships and collaborations. 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