Epinephrine Injection Make an Appointment Ask a Question Search Conditions This information has been reviewed and approved by Allidah Poole Hicks, RN, AE-C, MS (July 2014). Want to use this on your website? Fill out the content usage request form and then copy this code: Summary: Epinephrine Injection: The quick, easy-to-use shot that could save lives. What Is Epinephrine? It treats severe or life-threatening allergic reactions known as anaphylaxis. Anaphylaxis can occur after exposure to allergens such as: Food (like milk, eggs, shellfish and peanuts) Insect stings Latex Medications When to Use an Epinephrine Injection During severe allergic symptoms including: Difficulty swallowing or drooling because you can't swallow Difficulty breathing, chest pains or tightness Persistent vomiting Persistent diarrhea How to Use an Epinephrine Injector* Grip the epinephrine pen firmly and remove safety cap. Swing and push the pen into the middle of the outer thigh at a 90° angle. Keep the pen pressed firmly against the thigh for 10 seconds. Remove the pen and massage the injection area. *Always follow the manufacturer's instructions for the specific injector you are using. After Use Get emergency medical help right away Make sure a second injection is nearby; if symptoms continue or come back within 10-15 minutes, you may need another dose Take (or give your child) an antihistamine Types of Epinephrine Common brands include: EpiPen® Auto-Injector EpiPen® Jr. Auto-Injector Adrenaclick® Auto-Injector Auvi-Q™ Auto-Injector Tips Carry your epinephrine with you at all times Carry an extra does for severe reactions You can inject through your clothing More Information on Epinephrine Anaphylaxis: Preparation & Treatment Video: How to Give Epinephrine Video: A Parent’s Experience with Epinephrine Video: The New Auvi-Q Injector Severe Reactions to Food More Common than Thought in Young Children Allergy Treatment Programs Pediatric Food Allergy Program Make an Appointment Find a Doctor You may use this infographic or our Ephinephrine Injection (pdf) with permission by completing our content usage request form.