Epinephrine Injection Make an Appointment Ask a Question Search Conditions This information has been reviewed and approved by Allidah Poole Hicks, RN, AE-C, MS (July 2014).Want to use this on your website? Fill out the content usage request form and then copy this code: Summary: Epinephrine Injection: The quick, easy-to-use shot that could save lives.What Is Epinephrine?It treats severe or life-threatening allergic reactions known as anaphylaxis. Anaphylaxis can occur after exposure to allergens such as:Food (like milk, eggs, shellfish and peanuts)Insect stingsLatexMedications When to Use an Epinephrine InjectionDuring severe allergic symptoms including:Difficulty swallowing or drooling because you can't swallowDifficulty breathing, chest pains or tightnessPersistent vomitingPersistent diarrhea How to Use an Epinephrine Injector*Grip the epinephrine pen firmly and remove safety cap.Swing and push the pen into the middle of the outer thigh at a 90° angle.Keep the pen pressed firmly against the thigh for 10 seconds.Remove the pen and massage the injection area.*Always follow the manufacturer's instructions for the specific injector you are using. After UseGet emergency medical help right awayMake sure a second injection is nearby; if symptoms continue or come back within 10-15 minutes, you may need another doseTake (or give your child) an antihistamine Types of EpinephrineCommon brands include:EpiPen® Auto-InjectorEpiPen® Jr. Auto-InjectorAdrenaclick® Auto-InjectorAuvi-Q™ Auto-Injector TipsCarry your epinephrine with you at all timesCarry an extra does for severe reactionsYou can inject through your clothing More Information on EpinephrineAnaphylaxis: Preparation & TreatmentVideo: How to Give EpinephrineVideo: A Parent’s Experience with EpinephrineSevere Reactions to Food More Common than Thought in Young ChildrenAllergy Treatment ProgramsPediatric Food Allergy ProgramMake an AppointmentFind a DoctorYou may use this infographic or our Ephinephrine Injection (pdf) with permission by completing our content usage request form.