Skip to content

Does Keto Diet Help Reverse Heart Failure with Preserved Ejection Fraction?

Search Clinical Trials

Trial Objectives

The purpose of this study is to learn if a low carbohydrate ketogenic diet, or keto diet, can treat obesity-related heart failure with preserved ejection fraction (HFpEF). Studies have shown that weight loss through gastric bypass and calorie restriction can improve heart function. To see if a low carbohydrate diet works similarly, participants will follow a keto diet and be monitored for seven months.

Who Can Participate

  • Adults age 21-80 who meet clinical signs and symptoms of heart failure
  • Patients who received a right heart catheterization (RHC) and cardiopulmonary exercise test within the last 6 months
  • Patients who meet abdominal obesity with BMI > 30 kg/m2 or have a waist circumference:
    • Men > 102 cm
    • Women > 88 cm
  • Patients must own and operate a smart phone or tablet with email capabilities.

Age: 21-80 Gender: Any

Estimated Time Commitment

Not Specified

Payment & Reimbursement

Payment: Provided

Travel Reimbursement: Not Available

Trial Contact

For more information, contact:

Maria Saucedo

Request More Information

Trial Location

National Jewish Main Campus, Denver, CO

Trial Sponsors

Rose Community Foundation Project/Program

Principal Investigators

Darlene Kim

Darlene Kim, MD, FACC


Marjorie Patricia George

Marjorie Patricia George, MD

Request more Information

By completing this form, you agree to learn more about this study and see if you qualify.

I would also like to receive periodic emails with health information, news and clinical research updates from National Jewish Health required