Alpha-1 Antitrypsin Deficiency
Alpha-1 Antitrypsin Deficiency (often called simply “Alpha-1”) is an inherited condition that can cause liver disease in people of all ages and can lead to lung disease in adults. Alpha-1 is one of the most common inherited disorders. It accounts for about one percent of all cases of chronic obstructive pulmonary disease (COPD) in the United States.
National Jewish Health in Denver, Colorado, is one of the best places in the world to be treated for the adult lung and liver disease caused by Alpha-1. Our program has been devoted to the care of families with Alpha-1 since 1981, and our doctors have been involved in nearly every new drug evaluated for Alpha-1 treatment.
Our doctors are researchers too, so you have access to the latest Alpha-1 clinical trials and most effective therapies.
Alpha-1 Care at National Jewish Health
At National Jewish Health, you’ll find:
- The latest in clinical trials
- A focused and integrated approach
- State-of-the-art diagnostic testing
- The latest and best therapies
- Rehabilitation services
- Continued follow-up to meet your changing needs
Learn more about the Alpha-1 Treatment Program.
Condition Information
Programs & Services
Our Specialists
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James K. O'Brien, MD, FACP, FCCP
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Irina Petrache, MD
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Robert A. Sandhaus, MD, PhD, FCCP
Call 1.877.CALL.NJH
Clinical Trials
Patient Stories
Living the Sweet Life with Alpha-1
Judy got the test for Alpha-1, and it came back positive. She began weekly augmentation therapy at National Jewish Health and has felt a great relief of her symptoms.