Alpha-1 Antitrypsin Deficiency

Alpha-1 Antitrypsin DeficiencyAlpha-1 Antitrypsin Deficiency (often called simply “Alpha-1”) is an inherited condition that can cause liver disease in people of all ages and can lead to lung disease in adults. Alpha-1 is one of the most common inherited disorders. It accounts for about one percent of all cases of chronic obstructive pulmonary disease (COPD) in the United States.


National Jewish Health in Denver, Colorado, is one of the best places in the world to be treated for the adult lung and liver disease caused by Alpha-1. Our program has been devoted to the care of families with Alpha-1 since 1981, and our doctors have been involved in nearly every new drug evaluated for Alpha-1 treatment.

Our doctors are researchers too, so you have access to the latest Alpha-1 clinical trials and most effective therapies.


Alpha-1 Care at National Jewish Health

At National Jewish Health, you’ll find:

  • The latest in clinical trials
  • A focused and integrated approach
  • State-of-the-art diagnostic testing
  • The latest and best therapies
  • Rehabilitation services
  • Continued follow-up to meet your changing needs.

Learn more about the Alpha-1 Treatment Program.

Condition Information
Conditions We Treat
Programs & Services
Programs and Services


We Are Open and Here for You: Our specialty care clinics for adults and children are open and ready to serve you. Your health is important, and that means taking care of your existing health care issues. Please note that as we schedule appointments, including necessary procedures, we’re taking every precaution possible to ensure it’s safe to see your doctor.

Patient Safety & Care


Our Patient Education Program at National Jewish Health provides many free educational opportunities and support groups to assist patients and caregivers with managing illnesses and chronic conditions.


Download Free Patient Education Materials

There are a number of written materials to support patient education at National Jewish Health. They include Understanding Booklets, Med Facts, Test Facts, Medication handouts and more. 

Reasons to Choose National Jewish Health

  • The leading respiratory hospital in the nation and the only one devoted fully to the treatment of respiratory and related illnesses
  • Ranked as one of the top two hospitals in pulmonology every year since U.S. News & World Report included this category in its annual “Best Hospitals” survey
  • Ranked in the top 1 percent of hospitals in the nation by HCAHPS
  • Physicians consistently recognized among the best in the nation by multiple services, including Best Doctors in America and Castle Connolly
  • Among the top 6 percent of organizations funded for research by the NIH, providing patients access to more than 300 active clinical trials
  • 121-year history of focus on care, research and education serving thousands of patients with lung, heart, immune and related disorders


Ask a Question | Insurance Information

Many patients who come to National Jewish Health are trying to find answers to ongoing health issues. Our doctors use advanced testing to accurately diagnose our patients’ conditions and determine the best treatment plan.

You can support National Jewish Health in a variety of ways. Learn about more ways to give to help us provide lifesaving care and groundbreaking research.


Living with COPD

Clinical Trials

For more than 100 years, National Jewish Health has been committed to finding new treatments and cures for diseases. Search our clinical trials.

Make an Appointment Call 1.877.CALL.NJH