Alpha-1 Antitrypsin Deficiency

Alpha-1 Antitrypsin DeficiencyAlpha-1 Antitrypsin Deficiency (often called simply “Alpha-1”) is an inherited condition that can cause liver disease in people of all ages and can lead to lung disease in adults. Alpha-1 is one of the most common inherited disorders. It accounts for about one percent of all cases of chronic obstructive pulmonary disease (COPD) in the United States.


National Jewish Health in Denver, Colorado, is one of the best places in the world to be treated for the adult lung and liver disease caused by Alpha-1. Our program has been devoted to the care of families with Alpha-1 since 1981, and our doctors have been involved in nearly every new drug evaluated for Alpha-1 treatment.

Our doctors are researchers too, so you have access to the latest Alpha-1 clinical trials and most effective therapies.


Alpha-1 Care at National Jewish Health

At National Jewish Health, you’ll find:

  • The latest in clinical trials
  • A focused and integrated approach
  • State-of-the-art diagnostic testing
  • The latest and best therapies
  • Rehabilitation services
  • Continued follow-up to meet your changing needs

Learn more about the Alpha-1 Treatment Program.

Condition Information
Conditions We Treat
Programs & Services
Programs and Services


Get the Care You Need: We are ready to help you stay healthy with many same-day appointments available and are taking every precaution to ensure your safety


Our Patient Education Program at National Jewish Health provides many free educational opportunities and support groups to assist patients and caregivers with managing illnesses and chronic conditions.


Download Free Patient Education Materials

There are a number of written materials to support patient education at National Jewish Health. They include Understanding Booklets, Med Facts, Test Facts, Medication handouts and more. 

Reasons to Choose National Jewish Health

  • The leading respiratory hospital in the nation and the only one devoted fully to the treatment of respiratory and related illnesses

  • Ranked #1 or #2 in Pulmonology by U.S. News & World Report for 26 consecutive years

  • Ranked in the top 5% of hospitals in the nation by HCAHPS

  • Physicians consistently recognized among the best in the nation by multiple services, including Best Doctors in America and Castle Connolly

  • Among the top 6% of organizations funded for research by the NIH, providing patients access to hundreds of active clinical trials

  • 124-year history of focus on care, research and education serving patients from around the world with lung, heart, immune and related disorders

Ask a Question | Insurance Information

Many patients who come to National Jewish Health are trying to find answers to ongoing health issues. Our doctors use advanced testing to accurately diagnose our patients’ conditions and determine the best treatment plan.

You can support National Jewish Health in a variety of ways. Learn about more ways to give to help us provide lifesaving care and groundbreaking research.


Living with COPD

Make an Appointment Call 1.877.CALL.NJH