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Research Histology and Pathology

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The Pathology Laboratory is a Morphology Core Facility, which provides histopathological and immunocytochemical support for clinicians and research investigators at National Jewish Health.

The facility provides quality control for morphologic studies, and optimizes use of supplies and equipment. Ongoing interaction of our personnel with each investigator facilitates communication regarding morphologic findings, histopathological interpretation, and new technical developments, thus increasing the efficiency of the research projects. 

Our personnel are experienced, dedicated technicians who are accustomed to serving specialized clinical and research needs. A full range of histologic routine and special staining procedures are available. Immunohistochemistry techniques also are offered. Expert advice is available regarding optimal staining methods for special projects.

 

Areas of Research and Clinical Pathology

Our areas of expertise include, but are not limited to:

  • Experimental Pathology - Animal models of inflammation and pathologic states and in human pulmonary diseases. We have extensive experience in the evaluation of development and resolution of pulmonary inflammation, fibrosis, and in animal "models" of asthma. In the past ten years we have also explored the involvement of chronic infection with atypical pathogens in the persistence of asthma. We have a long-standing interest in pulmonary vascular remodeling in pulmonary hypertension.
  • Digital Pathology – Scanning whole slides into high-resolution digital images for remote viewing, storage, sharing, and analysis. The images can be viewed on campus through a browser link, or copies can be made. Slides can be scanned at both 20x and 40x.


Major Capital Equipment

  • Leica Pearl Tissue Processor
  • Sakura VIP Tissue Processor
  • Sakura Embedding Center
  • Reichert -Jung Cryocut Cryostat
  • Leica Apero AT2 Whole Slide Scanner
  • Zeiss Light Microscope
  • Olympus Double-headed Light Microscope Equipped with Camera
  • Olympus Triple-headed Microscope
  • Leica Biocut Microtome
  • Leica Autocut Microtome
  • Leica Bond IHC/ISH Autostainer
  • Leica ST5020 H&E Autostainer

Consulting Pathologists

Contact Information

Pathology Facility
Hanley Building, Room F111
National Jewish Health
1400 Jackson St.
Denver, CO 80206
303.398.1163
Fax: 303.270.2240