Eczema: Symptoms Make an Appointment Refer a Patient Ask a Question People with symptoms of eczema tend to have dry, itchy and easily irritated skin. This can continue for years and may result in damage to the skin. They may have times when their skin is clear and other times when they have rash. Eczema in a Baby or Infant In babies with eczema symptoms, the rash appears most often on the cheeks, scalp, and the extensor (outer) aspects of the knees and elbows. Infant typically spares the diaper area. Eczema in Children With eczema in children, the creases of the knees and elbows are commonly affected. Other symptom sites include the neck and skin creases at the wrist and ankle and the top of the thighs. Eczema in Adults In adults with eczema symptoms, the atopic dermatitis rash often appears in and around the creases of the arms and legs, although sometimes the hands and feet are the only affected areas. Patients in any phase can sometimes develop a thickening of skin, called lichenification. However, this shows up more frequently in older children and adults than infants. In any phase, skin infections by bacteria and viruses can occur. There are many things that worsen the itching and rash of eczema (atopic dermatits). These are different for each person. It's important to work closely with your healthcare provider to try to figure out what makes your itching, rash, and other symptoms worse. What Causes Eczema? Eczema: Triggers Clinical Trials For more than 100 years, National Jewish Health has been committed to finding new treatments and cures for diseases. Search our clinical trials.