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WISPer Trial: Investigational New Treatment for IPF

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Trial Objectives


Idiopathic pulmonary fibrosis, or IPF, is a rare lung disease that causes scarring, or fibrosis, in the lungs, leading to difficulty breathing and other chronic symptoms. Researchers are evaluating a new medication, called MTX-463, to determine if it can safely and effectively reduce IPF symptoms over time.

Volunteers in this study will be randomly assigned to receive either the study medication or a placebo (a medication containing no active ingredient) as an infusion. At clinic visits, volunteers will complete questionnaires about their symptoms, receive physical exams and lung function tests, and provide blood samples. The data collected will help researchers determine if this new medication helps improve lung function over time.
 

Who Can Participate


Adults 40 years and older who were diagnosed with IPF in the previous 7 years and have a Forced Vital Capacity (FVC) of at least 45% predicted.
 

Age: 40+ Gender: Any

Estimated Time Commitment


Clinic visits every 4 weeks for up to 32 weeks

Payment & Reimbursement


Travel Reimbursement: Available

Trial Contact


For more information, contact:

Jane Baer
303.270.3864

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Trial Location


National Jewish Main Campus, Denver, CO

Trial Sponsors


Mediar Therapeutics

Principal Investigators

Michael P. Mohning

Michael P. Mohning, MD

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