Understanding the Role of Neutrophils in Asthma
Trial Objectives
Neutrophils are a type of white blood cells in the lung that drive several types of lung disease, yet are poorly understood. Researchers in the Neu-Lung Asthma study are investigating the role that these cells play in different types of asthma to better understand how neutrophils affect the disease.In this study, researchers will collect neutrophil samples from blood, the nose and the lungs from both healthy volunteers and those with severe asthma. Data collected during this study will help researchers better understand how these cells work and how they affect asthma. The samples collected also will be stored for potential use in future research.
Who Can Participate
People 7 to 80 years old who are either:
a) Healthy, with no history of asthma, severe lung disease or smoking OR
b) Have a diagnosis of severe asthma and have not smoked in the past year
Age: 7-80 Gender: Any
Estimated Time Commitment
One to four visits
Payment & Reimbursement
Payment: Provided
Travel Reimbursement: Not Available
Trial Location
National Jewish Main Campus, Denver, CO
Trial Sponsors
NIH
Principal Investigators
Max Seibold, PhD
Co-Investigators
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Ronina A. Covar, MD
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Vamsi P. Guntur, MD, MSc
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Michael E. Wechsler, MD, MMSc
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Pamela L. Zeitlin, MD, MPhil, PhD