Vasculitis: Symptoms Make an Appointment Refer a Patient Ask a Question Reviewed by Isabelle Amigues, MD, MS, RhMSUS (March 01, 2020) The symptoms of vasculitis depend on which blood vessels and organs are affected. If vasculitis is present in small capillaries, symptoms may be apparent in the fingers and toes. If vasculitis is present in medium to large blood vessels, symptoms may occur in the head and neck. Because vasculitis often affects several organs or even the entire body (systemic vasculitis), many people experience a variety of numerous symptoms or an overall feeling of illness which vary widely between individuals. General Vasculitis Symptoms: Shortness of breath or cough Fever Headache Loss of appetite Weight loss General aches and pains Night sweats Skin rashes Numbness Weakness (fatigue) A general feeling of malaise or illness Specific types of Vasculitis may have more pronounced Symptoms: Lesions, ulcers or red or purple spots on the skin Mottled skin coloration Lumps or nodules Abdominal pain Joint pain Bloody or dark urine Nasal and sinus congestion Vision problems Ignoring your symptoms may delay a proper diagnosis and treatment, which can result in long-term damage to the affected areas. It’s important to speak with your doctor if you experience symptoms that are uncommon or concerning to you. Vasculitis: Causes Vasculitis: Diagnosis Clinical Trials For more than 100 years, National Jewish Health has been committed to finding new treatments and cures for diseases. Search our clinical trials.