Symptoms Make an Appointment Refer a Patient Ask a Question Reviewed by Barbara Goldstein, MD (February 01, 2016) Because undifferentiated connective tissue (UCTD) disease can affect so many different parts of the body as an autoimmune disease, UCTD often has many symptoms. Common symptoms of undifferentiated connective tissue disease include: Weight loss Fatigue Low-grade fevers Rash Joint pain Joint swelling Color changes of hands and feet with cold exposure (known as Raynaud's disease) Dryness of the eyes Dryness of the mouth Lymph node swelling Muscle weakness Muscle pains Difficulty swallowing Heartburn Cough Shortness of breath Chest pain Causes Diagnosis Clinical Trials For more than 100 years, National Jewish Health has been committed to finding new treatments and cures for diseases. Search our clinical trials.
Reviewed by Barbara Goldstein, MD (February 01, 2016) Because undifferentiated connective tissue (UCTD) disease can affect so many different parts of the body as an autoimmune disease, UCTD often has many symptoms. Common symptoms of undifferentiated connective tissue disease include: Weight loss Fatigue Low-grade fevers Rash Joint pain Joint swelling Color changes of hands and feet with cold exposure (known as Raynaud's disease) Dryness of the eyes Dryness of the mouth Lymph node swelling Muscle weakness Muscle pains Difficulty swallowing Heartburn Cough Shortness of breath Chest pain Causes Diagnosis