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This information was reviewed and approved by Madison Hucke, BSN, RN (2/1/2026).

What is Esophageal Manometry?

The esophagus is the tube that goes from the mouth to the stomach. The esophageal manometry test measures how well the esophagus moves food and fluid from the throat to the stomach by measuring muscle contraction pressures produced by swallowing using a pressure-sensitive catheter.  Doctors often order manometry for patients who may have trouble swallowing, a cough, reflux, heartburn, or non-cardiac chest pain. A manometry is also ordered for pre-op evaluation for anti-reflux surgery and to obtain accurate measurements for impedance probe placement.

Preparing for the Test

Twenty-four hours before the tes, stop taking calcium channel blocker medication (e.g. verapamil, nifedipine, cardizem); nitrate medicine (e.g. isosorbide), Motilium (domperidone), Reglan (metaclopramide), bethanechol and baclofen.
Twelve hours before the test: stop taking benzodiazepines (e.g. valium, xanax).
Any of the above medications can affect how the esophagus behaves. You may resume these medications after the test. Do not eat or drink for two hours prior to testing.

During the Test

A specially trained medical professional will lubricate your nose with an anesthetic gel before passing the catheter through the nose. You will take sips of water to guide the catheter down the esophagus. Once this initial probe placement has been achieved, you will be asked to lie down on your left side. Esophageal function will be evaluated by having you swallow small amounts of liguid, both lying down and sitting up.

Testing takes approximately 20-30 minutes. If an impedance probe is ordered, it will be placed after completion of the manometry.

After the test

  • You can resume normal diet and activities.
  • You may have a sore throat, which is normal. Over-the-counter lozenges and/or saltwater gargles can help.
  • The study must be analyzed and then interpreted; this process usually takes between four and six weeks. After it is interpreted, someone from National Jewish Health will call you with the results. You can also call National Jewish Health to check on the status of your results, if you wish (303.398.1355).
  • If you think you may be experiencing any unusual symptoms or side effects, call your doctor.

© Copyright Revised 2026.