Clinical Data & Specimens Make an Appointment Ask a Question Refer Patient Clinical Data Questionnaire: Each participant completes a private interviewer-administered questionnaire to obtain demographics, medical history, clinical symptoms and occupational and exposure history. Clinical data: Each participant is asked to provide consent to review medical evaluation results and tests. Radiological Data: Each clinical center has obtained copies of CT scan images from their respective radiology department's CT scanners in a format that has de-identified participant-specific data. The DCC has copies of these CT scans available to researchers. Specimens The following table lists the current biological specimen inventory available to researchers. Note: Transbronchial biopsy tissue is also available from 216 participants (3 slides each) Storage Specifications Plasma Plasma samples are split into cryovials – 0.5 ml per vial. They are stored at -80°C in 2 inch fiberboard boxes. Isolated DNA DNA has been isolated from the blood and separated into aliquots at a volume of 0.1ml. Please note that the concentration of DNA (µg/ml) per aliquot is variable and requests will be made per volume, not concentration. DNA vials are labeled with printed labels and stored at -80 °C. Cryopreserved Cells Cells are split into 5 million cells per aliquot. They are stored in cryogenic safe plastic boxes in liquid nitrogen vapor tanks. BAL Cryopreserved Cells Cells are split into 10 million cells per aliquot. They are stored in cryogenic safe plastic boxes in liquid nitrogen vapor tanks. BAL Fluid BALF samples are split into cryovials – 3.5 ml per vial. They are stored at -80 °C in the 2 inch fiberboard boxes. Specific processing procedures and storage conditions can be found in the Beryllium BioBank Protocol. Data & Specimen Requests Investigators wishing to use BBB data and/or specimens to investigate hypotheses which are directly associated to patients with chronic beryllium disease should submit a written proposal. All proposals for acquisition of specimens and clinical data will be reviewed based on the statistical plans and power analysis as well as evaluating it for merit and feasibility. For requests, please contact: Lisa A. Maier, MD, MSPH, FCCP Beryllium BioBank National Jewish Health 1400 Jackson St., G204 Denver, CO 80206 MaierL@NJHealth.org or BarkesB@NJHealth.org