Symptoms Make an Appointment Refer a Patient Ask a Question Reviewed by Maura Robinson (May 01, 2012) Simple pneumoconiosis, usually detectable on chest imaging, may produce no symptoms and very little loss of lung function. The more complicated and severe form of pneumoconiosis known as Progressive Massive Fibrosis (PMF) leads to an increasing loss of lung function and respiratory symptoms of shortness of breath and cough with phlegm. Other organs, particularly the heart, may be affected. Diagnosis Clinical Trials For more than 100 years, National Jewish Health has been committed to finding new treatments and cures for diseases. Search our clinical trials.