Reviewed by the National Institute of Allergy and Infectious Diseases

There are two types of mastocytosis:

  • Cutaneous mastocytosis, or skin mastocytosis. This occurs when mast cells infiltrate the skin.

  • Systemic mastocytosis, which occurs when too many mast cells accumulate in the tissues. It can affect organs such as the liver, spleen, small intestine, and even bone marrow.

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