Congestive Heart Failure: Treatment Make an Appointment Refer a Patient Ask a Question Reviewed by Andrew M. Freeman, MD, FACC, FACP (December 01, 2012) A variety of medicines are available to help treat congestive heart failure. Some of the most frequently prescribed medications include: Diuretics: (water or fluid pills) Reduce fluid buildup in the lungs and body swelling. ACE inhibitors: Decrease blood pressure and lessen any strain on the heart. They may also help lessen the chance of a heart attack. Aldosterone Antagonists: Cause the body to dispose of excess salt and water in urine, helping lower the volume of blood that the heart must pump and lessening its workload. Angiotensin Receptor Blockers: Help decrease blood pressure and relax blood vessels Beta Blockers: Decrease heart rate and blood pressure. Isosorbide Dinitrate/Hydralazine Hydrochloride: Relax blood vessels. Digoxin: Makes the heart beat stronger. If you have trouble breathing, you may be given an oxygen tank to make breathing easier and more productive. Congestive Heart Failure: Diagnosis Congestive Heart Failure: Lifestyle Management Clinical Trials For more than 100 years, National Jewish Health has been committed to finding new treatments and cures for diseases. Search our clinical trials.