Reviewed by Lisa A. Maier, MD, MSPH, FCCP

About Beryllium Sensitization

Beryllium sensitization is an allergy to beryllium that may develop after a susceptible person breathes beryllium dust or fumes, or if beryllium penetrates the skin through an open cut or dermal exposure. Individuals that have a certain gene called HLA-DPB Glu69 are susceptible and more likely to become sensitized after exposure to beryllium.

In individuals with beryllium sensitization, the immune system sees beryllium as a foreign substance and responds by generating a population of immune cells in the bloodstream that react to beryllium. These cells can be found in the blood using a test called the beryllium lymphocyte proliferation test (BeLPT).


Clinical Trials

For more than 100 years, National Jewish Health has been committed to finding new treatments and cures for diseases. Search our clinical trials.