Allergic Bronchopulmonary Aspergillosis (ABPA) Make an Appointment Find a Doctor Ask a Question Reviewed by Eugene Choo, MD (July 01, 2012) Allergic bronchopulmonary aspergillosis (ABPA) is an allergic reaction in the lungs caused by the growth of a fungus, Aspergillus. This fungus causes inflammation (swelling), airway obstruction and mucus plugging. Eventually, this can lead to bronchiectasis (abnormal widening of the bronchial tubes), fibrosis (scarring) of the lungs and impaired respiratory function. Symptoms ABPA usually occurs in individuals with asthma or cystic fibrosis. The typical symptoms are asthma, coughing that produces brown mucus and occasionally blood, fever and a general sense of not feeling well. The diagnostic evaluation includes blood tests such as eosinophils (white blood cell count) and antibody levels for Aspergillus. Skin testing for Aspergillus is helpful, as is a high resolution CT scan of the chest. Treatment Treatment of ABPA typically includes oral steroids (such as prednisone) for several weeks, sometimes in conjunction with an antifungal medication Programs & Services Respiratory Treatment Programs Clinical Trials For more than 100 years, National Jewish Health has been committed to finding new treatments and cures for diseases. Search our clinical trials.