MIS-C Signs & Symptoms Make an Appointment Refer a Patient Ask a Question Reviewed by Donald Y M Leung, PhD, MD, Pamela L. Zeitlin, MD, MPhil, PhD (May 26, 2020) Fever – high for seven or more days in an infant or more than four days in older children, with no other reason for the fever Red, cracked or swollen lips Rash Pink or reddish eyes Swollen lymph nodes – on one side of the neck Swollen hands and feel Sharp abdominal pain Vomiting Diarrhea Respiratory symptoms When to Call the Doctor about MIS-C? Call your doctor if your child has a fever (lasting for seven or more days in infants and four or more days in older children). Mention other symptoms your child is experiencing. MIS-C Treatment Clinical Trials For more than 100 years, National Jewish Health has been committed to finding new treatments and cures for diseases. Search our clinical trials.