SSA/Ro, Sjogren's Disease Antibody
Test Code
SSA
Description
SSA (or Ro) is comprised of two protein antigens of 52 kDa and 60 kDa that combine with RNA. SSA antibodies are found in 40-60% of patients with Sjogren’s disease and in 25- 35% of patients with ANA positive Systemic Lupus Erythematosus (SLE or lupus). SSA antibodies can occur alone or together with SSB antibodies.
This assay is intended for the semi-quantitative detection of SSA antibodies in human serum.
The presence of these antibodies can be used in conjunction with clinical findings and other laboratory tests to aid in the diagnosis of SLE and related connective tissue diseases, such as Sjogren’s disease.
Collect
Serum separator tube or a plain red top tube.
Pediatric Collection
Minimum Volume: 0.5mL serum
Unacceptable Conditions
Plasma, lipemic, grossly hemolyzed, microbially contaminated specimens, or specimens with visible particulates should not be used.
Storage Transport Temp
Frozen. Send serum Priority Overnight via FedEx and in a well insulated container on dry ice.
Stability
Up to 8 hours ambient or 48 hours refrigerated at 2-8°C. Freeze at or below -20°C for longer storage or shipping.
Performed
Weekly
Methodology
Enzyme-linked immunoabsorbent assay (ELISA)
Turnaround Time
7-9 Business Days
Department
Immunology Lab - Diagnostic
Synonyms
Sjogren’s SSA; ELISA (Sjogren’s Ab SSA), SSAB, Ro
Study Offerings
CAP/CLIA
Related Tests
SSB, ANA, ENA, ENA6, Sjogren’s antibody, anti-SSA, Ro-52, Ro-60, anti-SSB (SSAB/SSBB)
Reference Interval
Negative <20, Weak Positive 20-39, Moderate Positive 40-80, Strong Positive >80 units.
CPT Code
86235
New York Approved
No: Run with Waiver
FDA
LDT