Advanced Diagnostic Laboratories

Interleukin 13 (IL-13)

Test Code

IL13

Description

Interleukin-13 (IL-13) is a Type 2 (Th2) cytokine with immunomodulatory properties including the protection against extracellular parasites as well as to the pathogenesis of asthma and many allergic inflammatory diseases such as atopic dermatitis. In the lung, IL-13 is the central mediator of allergic asthma, where it contributes to mucus hyperproduction, airway hyperresponsiveness and fibrosis.

Collect

Plasma from a lavender top (K2- EDTA) tube is the only acceptable sample type. The EDTA collection tube must be completely filled with blood to ensure the correct blood to anticoagulant ratio. Invert tube several times for thorough mixing of blood anticoagulants. Keep the EDTA tube filled with blood on ICE until centrifugation.

Patient Prep

Within 30 (±5) minutes of venipuncture, centrifuge the collection tube at 1600 (± 200) x g (rcf) at 4°C (± 2°C) for 15 (±1) minutes. Transfer the cell-free plasma to a clean cryogenic storage tube and immediately store the cryogenic tube at -20°C, or freeze at -60°C or below in an ultra-low freezer.

Preferred volume: 1 mL plasma
Minimum volume: 0.5 mL plasma

Pediatric Collection

Minimum volume: 0.25 mL plasma/p>

Unacceptable Conditions

Thawed samples or samples stored at room temperature prior to shipment.

Storage Transport Temp

Ship samples overnight in a well-insulated container on dry ice.

Stability

-60°C or below in an ultra-low freezer - up to 1 year

Notes

Additional testing may be needed for less than perfect samples on confirmatory testing/reflex testing.

To prevent unnecessary delays in testing, please send one aliquot per test request.

Performed

Monday - Friday

Methodology

Luminex bead based assay

Turnaround Time

Up to 4 weeks

Department

Complement Lab

Synonyms

Interleukin 13, IL-13, IL 13, Complement, Cytokines, TH2, Type 2 Cytokines

Study Offerings

Not offered

Related Tests

THPA, THPB, TH1, and TH2