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Advanced Diagnostic Laboratories

Immunoglobulin E, Total


Test Code

TIGE

Description

Total IgE is an in-vitro test for the quantitative measurement of the quantity of circulating IgE in human serum or plasma samples. IgE antibodies appear as a result of sensitization to allergens. The measurement of circulating total IgE assists the clinical diagnosis of IgE-mediated allergic disorders. Elevated levels of circulating total IgE are usually seen in patients suffering from extrinsic asthma, hay fever or atopic eczema. IgE antibodies appear in human serum and plasma as a result of sensitization to a specific allergen. Measurement of circulating specific IgE antibodies provides an objective assessment of sensitization to an allergen. In general, low IgE antibody levels indicate a low probability of clinical disease, whereas high antibody levels to an allergen show good correlation with clinical disease.