Advanced Diagnostic Laboratories

Collect

Serum from a plain red top is the only acceptable sample type.
Gel barrier tubes are not acceptable.

Specimen Preparation

Allow blood to clot at room temp or 37°C for 20 to 60 minutes. Centrifuge to thoroughly remove cells and immediately transfer cell-free serum to a fresh tube and freeze the cell-free serum on dry ice or at -70°C.
Preferred volume: 1 mL

Pediatric Collection

Minimum volume: 500 µL serum, frozen

Unacceptable Conditions

Thawed specimen.

Storage Transport Temp

Send frozen serum Priority Overnight via FedEx and in a well insulated container on dry ice.

Stability

Frozen at -70°C: 1 year

Methodology

Turbidimetry and Photometry

Reported

up to 4 weeks

Department

Complement Lab

Synonyms

Subclasses, IgG1, IgG2, IgG3, IgG4, total IgG, subclasses;IGSUB

Reference Interval

 

TEST CODE	AGE	REFERENCE RANGE (mg/dL)
IGG1	0-2	194-842
	2-4	315-945
	4-6	306-945
	6-8	288-918
	8-10	432-1020
	10-12	423-1060
	12-14	342-1150
	14-18	315-855
	18+	278.5 – 849.9
IGG2	0-2	22.5-300
	2-4	36.0-225
	4-6	60.5-345
	6-8	44.0-375
	8-10	72.0-430
	10-12	76.0-355
	12-14	100-455
	14-18	64.0-495
	18+	172.2-694.7
IGG3	0-2	18.6-85.3
	2-4	17.3-67.6
	4-6	9.9-122.1
	6-8	15.5-85.3
	8-10	12.7-85.3
	10-12	17.3-173
	12-14	28.3-125
	14-18	23.0-196
	18+	13.53-167.4
IGG4	0-2	0.5-78.4
	2-4	1.0-53.7
	4-6	1.8-112.5
	6-8	0.4-99.2
	8-10	1.9-93.2
	10-12	1.6-115
	12-14	3.7-136
	14-18	11.0-157
	18+	3.41-142.8
Total IGG	0-3M	250-1200
	3M-2Y	286-1680
	2-4	341-1960
	4-20	528-2190
	20+	700-1620

 

CPT Code

82787x4, 82784