Advanced Diagnostic Laboratories

Collect

Plain red top or SST tube.

Specimen Preparation

Onsite [NJH]: Transport to lab within 1 hour.
Offsite: Separate serum from cells within 2 hours by centrifuge and aliquot into a labeled polypropylene or similar plastic tube.
Preferred volume: 1 mL serum

Pediatric Collection

Minimum volume: 0.15 mL serum

Unacceptable Conditions

NA

Storage Transport Temp

Offsite: Send frozen serum Priority Overnight via FedEx and in a well insulated container on dry ice.

Stability

Stability after cell separation:      
4 hours at RT (15-25°C)
8 days at 2-8°C
3 months frozen at ≥ -20°C

Performed

Monday - Friday

Methodology

Turbidimetry

Reported

4 hours

Department

Core Lab

Synonyms

Complement (C4 Level);Acquired Angiodema (C4 Level);Hereditary Angiodema (C4 Level);Angiodema (C4 Level);Nephelometry (C4 Level)

Related Tests

Acquired Angiodema: C1-INH function (CEIF), C1-INH level (CEIQ), C1q level (C1Q), C1-inhibitor autoantibody (CEIAP)

Reference Interval

C4 Level	Human
	Male	Female
	mg/dL
Newborn - 2 months	13-38	13-38
3 months - 19 years	11-61	11-61
20+ years	19-52	19-52

CPT Code

86160