Complement 3 Level
Test Code
C3
Description
Complement Component C3c and C4c - Decreased concentrations of both C3 and C4 suggest activation of the classical pathway, whereas decreased concentration of just C3 suggests activation of the alternative pathway. Both complement factors may be used to monitor activity of patients with systemic lupus erythematosus (SLE) and immune complex-induced vasculitis.
Collect
Plain red top or SST tube.
Pediatric Collection
Minimum volume: 0.15 mL serum
Unacceptable Conditions
NA
Storage Transport Temp
Offsite: Send frozen serum Priority Overnight via FedEx and in a well insulated container on dry ice.
Stability
Stability after cell separation:
4 hours at RT (15-25°C)
8 days at 2-8°C
3 months frozen at ≥ -20°C
Performed
Monday - Friday
Methodology
Turbidimetry
Turnaround Time
4 hours
Department
Core Lab
Synonyms
Complement (C3 Level);Nephelometry (C3 Level)
Study Offerings
Not offered
Reference Interval
C3 Level |
Human |
|
Male |
Female |
|
mg/dL |
||
Newborn - 1 month |
70-196 |
70-196 |
2 months - 11 months |
69-201 |
69-201 |
1 year - 19 years |
70-206 |
70-206 |
20+ years |
66-162 |
66-162 |
CPT Code
86160
New York Approved
FDA Approved or Cleared
FDA
Approved or Cleared