Skip to content

Rose Laboratory

Rose Laboratory

We welcome collaborators interested in diagnosis, treatment and prevention of occupational and environmental lung diseases.

I am a Professor of Pulmonary and Occupational Medicine with a master’s degree in public health. I have been a member of the academic faculty in the Departments of Medicine at National Jewish Health and the University of Colorado School of Medicine for over 35 years. I have an adjunct faculty appointment in the Department of Environmental and Occupational Health at the Colorado School of Public Health. My clinical and research interests focus on diagnosis, treatment, exposure assessment, and prevention of occupational and environmental lung diseases including the pneumoconioses (silicosis and coal worker’s pneumoconiosis) and those related to military deployment in Southwest Asia. In addition to my Occupational and Environmental Lung Disease clinical practice, I have had sustained federal funding for clinical research in these areas as well as national leadership positions to define research priorities and clinical guidelines. I am committed to training the next generation of clinician-educators and physician-scientists, and continue to build multi-institutional clinical and research programs and collaborations in these areas of interest.

     

Resources & Services

  • Center for Deployment-related Lung Disease: The Center team is focused on clinical care for veterans and contractors with persistent respiratory symptoms following military deployment to Southwest Asia and Afghanistan.   Research on deployment-related respiratory diseases includes epidemiology, exposure assessment, risk factors, diagnosis, treatment, and longitudinal outcomes in previously deployed military personnel.
  • Miners Clinic and related clinical/research programs on silicosis, Coal Worker’s Pneumoconiosis, and other dust diseases of the lung: The Miners Clinic at National Jewish Health is a federally funded program that provides medical screening, referral, benefits counseling and Black Lung exams for western miners.  Our Pneumoconiosis research focuses on the epidemiology, pathogenesis, mineralogy, histopathology, longitudinal outcomes and prevention of pneumoconiosis in U.S. miners, uranium industry workers, engineered stone fabricators and other exposed occupational groups.
  • Occupational and Environmental Lung Disease Clinic:  This subspecialty clinic centers on the diagnosis, treatment, counseling, and exposure assessment/control for environmental and occupational lung diseases, particularly pneumoconioses (e.g., silicosis, silicosarcoidosis, coal worker’s pneumoconiosis, and Dept. of Labor Black Lung exams), and post-9/11 deployment-related respiratory diseases.
Cecile S. Rose

Cecile S. Rose, MD, MPH

Current Projects 

Research Interests

Dr. Rose leads funded collaborative research projects on mining-related lung diseases including silicosis and coal worker’s pneumoconiosis; silicosis and silicosarcoidosis in stone fabricators; and diagnosis, treatment and pathogenesis of respiratory diseases from hazardous exposures during military deployment.  View Current Projects

Clinical Interests

Dr. Rose has a long-standing interest in occupational and environmental lung diseases. She has particular expertise in military deployment-related respiratory diseases, silicosis, coal worker’s pneumoconiosis, silicosarcoidosis and hypersensitivity pneumonitis (HP) including diagnosis, causation assessment, management and prevention.

Lab Personnel

Collaborators

  • Meehan, Richard (NJH)
  • Carlyne Cool, MD (University of Colorado)

  • Camille Moore, PhD (NJH)

  • Robert Cohen, MD (University of Illinois at Chicago)

  • Leonard Go, MD (University of Illinois at Chicago)

  • Kirsten Almberg, PhD (University of Illinois at Chicago)

  • Emily Sarver, PhD (Virginia Polytechnic Institute)

Publications

View all Publications

  • Rose CS, Moore CM, Zell-Baran LM, Krefft S, Wolff J, Pang K, Parr J, Cool C. Small airways and airspace inflammation and injury distinguish lung histopathology in deployed military personnel from healthy and diseased lungs. Hum Pathol. 2022 Jun;124:56-66. doi: 10.1016/j.humpath.2022.02.014. Epub 2022 Feb 28. PMID: 35240130.
  • Hua JT, Cool CD, Lowers HA, Go LHT, Zell-Baran LM, Sarver EA, Almberg KS, Pang KD, Majka SM, Franko AD, Vorajee NI, Cohen RA, Rose CS. Characterizing Lung Particulates Using Quantitative Microscopy in Coal Miners With Severe Pneumoconiosis. Arch Pathol Lab Med. 2024 Mar 1;148(3):327-335. doi: 10.5858/arpa.2022-0427-OA. PMID: 37270802; PMCID: PMC11542675.
  • Zell-Baran LM, Krefft SD, Strand M, Rose CS. Longitudinal changes in lung function following post-9/11 military deployment in symptomatic veterans. Respir Med. 2024 Jun;227:107638. doi: 10.1016/j.rmed.2024.107638. Epub 2024 Apr 17. PMID: 38641121.
  • Zell-Baran LM, Hua JT, Rose CS. Silicosis in Western U.S. Metal and Nonmetal Miners, 2002-2023. Am J Respir Crit Care Med. 2024 Mar 15;209(6):756-758. doi: 10.1164/rccm.202310-1846LE. PMID: 38271487
  • Lowers H, Zell-Baran L, Arslan Z, Moore CM, Rose C. Particle Morphology and Elemental Analysis of Lung Tissue from Post-9/11 Military Personnel with Biopsy-Proven Lung Disease. International Journal of Environmental Research and Public Health. 2024; 21(1):91. https://doi.org/10.3390/ijerph21010091
  • Hua JT, Zell-Baran LM, Moore CM, Rose CS. Racial Differences in Respiratory Impairment, Pneumoconiosis, and Federal Compensation for Western U.S. Indigenous Coal Miners. Ann Am Thorac Soc. 2023 Nov 2. doi: 10.1513/AnnalsATS.202305-496OC. PMID: 37916934.