Lahm Lab

Publications

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Frump AL, Albrecht ME, Yakubov B, Breuils Bonnet S, Nadeau V, Tremblay E, Potus F, Omura J, Cook T, Fisher A, Rodriguez BE, Brown RD, Stenmark KR, Rubinstein CD, Krentz K, Tabima DM, Li R, Sun X, Chesler NC, Provencher S, Bonnet S, Lahm T. 17β-estradiol and estrogen receptor-α protect right ventricular function in pulmonary hypertension via BMPR2 and apelin. J Clin Invest. 2021 Mar 15;131(6):e129433. doi: 10.1172/JCI129433. PMID: 33497359

Lahm T, Hess E, Barón AE, Maddox TM, Plomondon ME, Choudhary G, Maron BA, Zamanian RT, Leary PJ. Renin-Angiotensin-Aldosterone System Inhibitor Use and Mortality in Pulmonary Hypertension: Insights from the Veterans Affairs CART Database. Chest. 2021 Apr;159(4):1586-1597. doi: 10.1016/j.chest.2020.09.258. PMID: 33031831

Tello K, Richter MJ, Yogeswaran A, Ghofrani HA, Naeije R, Vanderpool R, Gall H, Tedford RJ, Seeger W, Lahm T. Sex Differences in Right Ventricular-pulmonary Arterial Coupling in Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. 2020 Oct 1;202(7):1042-1046. PMID: 32501730

Frump AL, Selej MA, Wood J, Albrecht M, Yakubov B, Petrache I, Lahm T. Hypoxia up-regulates estrogen receptor β in pulmonary artery endothelial cells in a HIF-1α dependent manner. Am J Resp Cell Mol Biol. 2018 Jul;59(1):114-126. PMID: 29394091

Lahm T, Albrecht M, Fisher AJ, Selej M, Patel N, Brown JA, Justice MJ, Brown MB, Van Demark M, Trulock KM, Dieudonne D, Reddy JG, Presson RG, Petrache I. 17-Beta Estradiol Attenuates Hypoxic Pulmonary Hypertension Via Estrogen Receptor-Mediated Effects. Am J Respir Crit Care Med. 2012 May 1;185(9):965-80. PMID: 25713318

Krishnan S, Stearman RS, Zeng L, Fisher AJ, Mickler EA, Rodriguez BH, Simpson ER, Cook TG, Slaven JE, Ivan M, Geraci MW, Lahm T, Tepper RS. Transcriptomic Modifications in Developmental Cardiopulmonary Adaptations to Chronic Hypoxia Using a Murine Model of Simulated High Altitude Exposure. Am J Physiol Lung Cell Mol Physiol. 2020. doi:10.1152/ajplung.00487.2019. PMID: 32639867