Abstracts available at Pub Med.

Zhang W, Case S, Bowler RP, Martin RJ, Jiang D, Chu HW. Cigarette smoke modulates PGE2 and host defense against Moraxella catarrhalis infection in human airway epithelial cells. Respirology 2011;16:508–516. Abstract

Wu Q, Jiang D, Minor MN, Martin RJ, Chu HW. In vivo function of airway epithelial TLR2 in host defense against bacterial infection. Am J Physiol Lung Cell Mol Physiol 2011;300:L579–586. Abstract

Simon GC, Martin RJ, Smith S, Thaikoottathil J, Bowler RP, Barenkamp SJ, Chu HW. Up-regulation of MUC18 in Airway Epithelial Cells by IL-13: Implications in Bacterial Adherence. Am J Respir Cell Mol Biol 2011;44:606–613. Abstract

Gally F, Di YP, Smith SK, Minor MN, Liu Y, Bratton DL, Frasch SC, Michels NM, Case SR, Chu HW. SPLUNC1 promotes lung innate defense against Mycoplasma pneumoniae infection in mice. Am J Pathol 2011;178:2159–2167. Abstract

Wang Y, Voelker DR, Lugogo NL, Wang G, Floros J, Ingram JL, Chu HW, Church TD, Kandasamy P, Fertel D, Wright JR, Kraft M. Surfactant Protein-A is Defective in Abrogating Inflammation in Asthma. Am J Physiol Lung Cell Mol Physiol 2011;301:L598–606. Abstract

Case SR, Martin RJ, Jiang D, Minor MN, Chu HW. MicroRNA-21 inhibits TLR2 agonist-induced lung inflammation in mice. Exp Lung Res 2011;37:500–508. Abstract

Thaikoottathil J, Chu HW. MAPK/AP-1 activation mediates TLR2 agonist-induced SPLUNC1 expression in human lung epithelial cells. Molecular Immunology 2011;49:415–412. Abstract

Kosmider B, Messier EM, Chu HW, Mason RJ. Human Alveolar Epithelial Cell Injury Induced by Cigarette Smoke. PLoS One 2011;6:e26059. Abstract

Gally F, Smith S, Minor MN, Chu HW. Heat Shock Factor 1 protects against lung Mycoplasma pneumoniae infection in mice. J Innate Immunity 2012;4:59­–68. Abstract

Wu Q, Jiang D, Chu HW. Cigarette smoke induces growth differentiation factor 15 production in human lung epithelial cells: implication in mucin overexpression. Innate Immunity 2011, Dec 16. [Epub ahead of print] Abstract

Wu Q, Jiang D, Smith S, Thaikoottathil J, Martin RJ, Bowler RP, Chu HW. IL-13 dampens human airway epithelial innate immunity through induction of interleukin-1 receptor associated kinase M. J Allergy Clin Immunol 2012;129:825–833. Abstract

Thaikoottathil JV, Martin RJ, Di PY, Minor M, Case S, Zhang B, Zhang G, Huang H, Chu HW. SPLUNC1 Deficiency Enhances Airway Eosinophilic Inflammation in Mice. Am J Respir Cell Mol Biol 2012 Apr 12. [Epub ahead of print] Abstract

Seshadri S, Lin DC, Rosati M, Carter RG, Norton JE, Suh L, Kato A, Chandra RK, Harris KE, Chu HW, Peters AT, Tan BK, Conley DB, Grammer LC, Kern RC, Schleimer RP. Reduced expression of antimicrobial PLUNC proteins in nasal polyp tissues of patients with chronic rhinosinusitis. Allergy 2012;67:920-928. Abstract

Chu HW, Gally F, Thaikoottathil J, Janssen-Heininger YM, Wu Q, Zhang G, Reisdorph N, Case S, Minor M, Smith S, Jiang D, Michels N, Simon G, Martin RJ. SPLUNC1 regulation in airway epithelial cells: role of Toll-like receptor 2 signaling. Respir Res. 2010 Nov 5;11(1):155. Abstract

Michels NM, Chu HW, Lafasto SC, Case SR, Minor MN, Martin RJ. Mast cells protect against airway Mycoplasma pneumoniae under allergic conditions. Clin Exp Allergy 2010;40:1406-1413. Abstract

Gross CA, Bowler RP, Green RM, Weinberger AR, Schnell C, Chu HW. Beta2-agonists promote host defense against bacterial infection in primary human bronchial epithelial cells. BMC Pulm Med 2010;10:30. Abstract

Green R, Gally F, Keeney JG, Alper S, Gao B, Han M, Martin RJ, Weinberger AR, Case SR, Minor MN, Chu HW. Impact of cigarette smoke exposure on innate immunity: a Caenorhabditis elegans model. PLoS ONE 2009;4:e6860. Abstract

Ge XN, Chu HW, Minor MN, Case SR, Bosch DG, Martin RJ. Roflumilast increases Clara cell secretory protein in cigarette smoke-exposed mice. COPD: Journal of Chronic Obstructive Pulmonary Disease 2009;6:185–191. Abstract

Thaikoottathil J, Martin RJ, Zdunek J, Weinberger A, Rino JG, Chu HW. Cigarette smoke extract reduces VEGF in primary human airway epithelial cells. Eur Respir J 2009;33:835–843. Abstract

Wu Q, Martin RJ, Lafasto S, Efaw BJ, Rino JG, Harbeck RJ, Chu HW. Toll-like receptor 2 down-regulation in established mouse allergic lungs contributes to decreased mycoplasma clearance. Am J Respir Crit Care Med 2008:177:720–729. Abstract

Chu HW, Thaikoottathil J, Rino JG, Zhang G, Wu Q, Moss T, Refaeli Y, Bowler R, Wenzel SE, Chen Z, Zdunek J, Breed R, Young R, Allaire E and Martin RJ. Function and regulation of SPLUNC1 protein in mycoplasma infection and allergic inflammation. J Immunol 2007;179;3995–4002. Abstract

Martin RJ, Wexler RB, Day BJ, Harbeck RJ, Pinkerton KE and Chu HW. Interaction between cigarette smoke and mycoplasma infection: a murine model. J COPD 2006;3:3–8. Abstract