Hisert Laboratory Search Clinical Trials Find a Researcher Order a Test Our lab performs basic & translational research to understand the role of monocytes and macrophages in modulating airway inflammation in people with cystic fibrosis (CF). Lab Resources & Services The lab is located on the 5th floor of the Smith Building. Current Projects Characterization of macrophage populations in the CF airway, and investigations into how these cells modulate inflammation. How much heterogeneity is present in airway macrophage populations? Does the abundance of populations of macrophage shift during pulmonary exacerbations? How do various medications affect airway macrophages phenotypes? Identification of novel therapeutics / anti-inflammatory medications for people with CF (and other chronic inflammatory airways diseases) Investigations into the role of macrophages in susceptibility of people with CF to NTM infection. View Diagrams Katherine Hisert, MD, PhD + × Katherine Hisert, MD, PhD Katherine Hisert, MD, PhD, is a pulmonologist at National Jewish Health. Dr. Hisert is in the Division of Pulmonary, Critical Care and Sleep Medicine. Assistant Professor Division of Pulmonary, Critical Care & Sleep Medicine Department of Medicine View Full Profile Make an Appointment Personnel Principal Investigator: Katherine “Katie” Hisert, MD, PhD Post-doctoral fellow: Ari Simenauer, PhD Research Technicians: Alma Ochoa Krystin Skinner Collaborators Jerry Nick, MD Milene Saavedra, MD Ken Malcolm, PhD William Janssen, MD Eszter Vladar, PhD, Vladar Lab Will DePas, PhD, DePas Lab Publications Hisert KB*, Heltshe SL*, Pope C*, Jorth P, Wu X, Edwards RM, Radey M, Accurso FJ, Wolter DJ, Cooke G, Adam RJ, Carter S, Grogan B, Launspach JL, Donnelly SC, Gallagher C, Bruce JE, Stoltz D, Welsh MJ, Hoffman LR§, McKone EF§, Singh PK§. “Restoring CFTR function reduces airway bacterial burden and inflammation in people with CF and chronic lung infections.” AJRCCM, 195(12): 1617-1628 (2017), PMID: 28222269 *these authors contributed equally. §these authors contributed equally. Hisert KB, Liles WC, Manicone AM. “A flow cytometric method for isolating cystic fibrosis airway macrophages from expectorated sputum.” AJRCMB. 61(1): 42-50 (2019), PMID: 30742539. View All Publications