Abstracts available at Pub Med.

Gould, N.S., Gauthier, S., Kariya, C.T., Min, E., Huang, J., and Day, B.J. Hypertonic saline increases lung epithelial lining fluid glutathione and thiocyanate: Two protective CFTR-dependent thiols against oxidative injury. Respir. Res. 11:119, 2010. Abstract

Brechbuhl, H.M., Gould, N., Kachadourian, R., Riekhof, W.R., Voelker, D.R., and Day, B.J. Glutathione transport is a unique function of the ATP-binding cassette protein ABCG2. J. Biol. Chem. 285:16582-16587, 2010. Abstract

O’Neill, H.C., White, C.W., Veress, L.A., Hendry-Hofer, T.B., Loader, J.E., Min, E., Huang, J., Rancourt, R.C., and Day, B.J. Treatment with catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of sulfur mustard analog 2-chloroethyl ethyl sulfide (CEES). Free Radic. Biol. Med., 48:1188-1196, 2010. Abstract

Brechbuhl, H.M., Min, E., Kariya, C., Frederick, B., Raben, D., and Day, B.J. Select cyclopentenone prostaglandins trigger glutathione efflux and the role of ABCG2 transport. Free Radic. Biol. Med. 47:722-730, 2009. Abstract

Gould, N.S, White, C.W., and Day, B.J. A role for mitochondrial oxidative stress in sulfur mustard analog CEES-induced lung cell injury and antioxidant protection. J. Pharmacol. Exp. Ther.328:732-739, 2009. Abstract

Kariya, C., Chu, H.W., Martin, R., Huang, J., Leitner, H. and Day, B.J. Mycoplasma infection and environmental tobacco smoke inhibits glutathione adaptive responses and increase oxidative stress. Infect. Immun. 76:4455-4462, 2008.  

Dobis, D.R., Sawyer R.T., Gillespie M.M., Huang J., Newman L.S., Maier L.A. and Day B.J. Modulation of Lymphocyte Proliferation by Antioxidants in Chronic Beryllium Disease. Am. J. Respir. Crit. Care Med. 177:1002-1011, 2008. Abstract

Kariya, C., Leitner, H., Min, E., van Heeckeren, C., van Heeckeren, A., and Day, B.J. A role for CFTR in the elevation of glutathione levels in the lung by oral glutathione administration. Am. J. Physiol. Lung Cell. Mol. Physiol.292:L1590-L1597, 2007. Abstract

Tong, J.J., Schriner, S.E., McCleary, D., Day, B.J., and Wallace, D.C. Life extension through neurofibromin mitochondrial regulation and antioxidant therapy for neurofibromatosis-1 in Drosophila. Nature Genetics 39:476-485, 2007. Abstract

Velsor, L.W., Kariya C., Kachadourian, R., and Day, B.J. Mitochondrial oxidative stress in the lungs of cystic fibrosis transmembrane conductance regulator protein mutant mice. Am. J. Respir. Cell Mol. Biol. 35:579-586, 2006.  Abstract

Kachadourian, R and Day, B.J.  Flavonoid-induced glutathione depletion: potential implications for cancer treatment. Free Radic. Biol. Med. 41:65-76, 2006. Abstract

Velsor, L.W., Kovacevic, M., Goldstein, M., Leitner, H.M., Lewis, W., and Day, B.J. Mitochondrial oxidative stress in human hepatoma cells exposed to stavudine. Toxicol. Appl. Pharamcol. 199:10-19, 2004. Abstract

Day, B.J., van Heeckeren, A.M., Min, E., and Velsor, L., Role for CFTR in a glutathione response to bronchopulmonary pseudomonas infection. Infect. Immun. 72:2045-2051, 2004. Abstract

Kachadourian, R., Johnson, C.A., Min, E., Spasojevic, I., and Day, B.J. Flavin-dependent antioxidant properties of a new series of meso-N, N’-dialkyl-imidazolium substituted manganese (III) porphyrins.  Biochem. Pharmacol. 67:77-85, 2004. Abstract

Bowler, R.P., Velsor, L.W., Duda, B., Chan, E., Abraham, E., Ware, L.B., Matthay, M.A. and Day B.J. Pulmonary edema fluid antioxidants predict outcome in acute lung injury. Crit. Care Med. 31:2309-2315, 2003.  

Gauuan, P.J.F., Trova, M.P., Gregor-Boros, L., Bocckino, S.B., Crapo, J.D., and Day, B.J. Superoxide dismutase (SOD) mimetics: An SAR study of MnTBAP analogs. Bioorganic Med. Chem. Lett. 10:3013-3021, 2002.

Oury, T.D., Thakker, K., Chang, L.Y., Crapo, J.D. and Day, B.J. Attenuation of bleomycin-induced pulmonary fibrosis by a catalytic antioxidant metalloporphyrin. Am. J. Respir. Cell Mol. Biol. 25:164-169, 2001. Abstract

Velsor, L., van Heeckeran, A., and Day, B.J. Antioxidant imbalance in the lungs of the cystic fibrosis transmembrane conductance regulator protein mutant mouse. Am. J. Physiol. 281:L31-L38, 2001. Abstract

Milano, J. and Day, B.J. A catalytic antioxidant metalloporphyrin blocks hydrogen peroxide induced mitochondrial DNA damage. Nucleic Acid Res. 28:968-973, 2000. Abstract

Day, B.J., Patel, M., Calavetta, L., Chang, L.Y. and Stamler, J.S.  A mechanism for paraquat toxicity that involves nitric oxide synthase. Proc. Natl. Acad. Sci. 96:12760-12765, 1999. Abstract

Day, B.J., Batinic-Haberle, I., and Crapo, J.D.  Metalloporphyrins are potent inhibitors of lipid peroxidation. Free Rad. Biol. Med. 26:730-736, 1999. Abstract

Melov, S., Schneider, J.A., Day, B.J., Hinerfeld, D., Coskun, P., Mirra, S. S., Crapo, J.D. and Wallace, D.C. A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase. Nature Genetics 18:159-163, 1998. Abstract

Day, B.J., Fridovich, I. and Crapo, J.D.  Manganic porphyrins possess catalase activity and protect endothelial cells against hydrogen peroxide-mediated injury. Arch Biochem Biophys 347:256-262, 1997. Abstract

Day, B.J. and Crapo, J.D.  A metalloporphyrin superoxide dismutase mimetic protects against paraquat-induced lung injury, in vivo. Toxicol Appl Pharmacol 140:94-100, 1996. Abstract

Day, B.J., Shawen, S., Liochev, S.I. and Crapo, J.D.  A metalloporphyrin superoxide dismutase mimetic protects against paraquat-induced endothelial cell injury, in vitro. J Pharmacol Exp Ther 275:1227-1232, 1995. Abstract


Books, Reviews, Commentaries and Editorials

Gould, N.S. and Day B.J. Targeting maladaptive glutathione responses in lung disease. Biochem. Pharmacol. 81:187-193, 2011.

Day, B.J. Catalase and glutathione peroxidase mimetics. Biochem Pharmacol 77:285-296, 2009.

Day, B.J. Antioxidants as potential therapeutics for lung fibrosis. Antiox Redox Sig, 10:355-370, 2008.

Lietner, H., Kachadourian, R., and Day, B.J. Harnessing drug resistance: Using ABC transporter proteins to target cancer cells. Biochem Pharmacol 74:1677-1685, 2007.

Day, B.J. Catalytic antioxidants: a radical approach to new therapeutics. Drug Disc Today 9:557-566, 2004.

Lewis, W., Copeland, W., and Day, B.J. Mitochondrial DNA depletion, oxidative stress and mutation: mechanisms of dysfunction from nucleoside reverse transcriptase inhibitors. Lab Invest 81:777-790, 2001.

Patel, M. and Day, B.J.  Metalloporphyrin class of catalytic antioxidants. Trends Pharm Sci. 20:359-364, 1999.