Kathryn Haskins, PhD

Kathryn Haskins
Professor
Research AreasResearch Areas
  • Autoimmunity/Rheumatology
  • Basic Immunology
  • Diabetes, Type-1

Special Interests

Research Interests

T cell immunology, autoimmunity, type 1 diabetes. Our research is focused on the mechanisms and regulation of pathogenesis in the NOD mouse model of type 1 diabetes (T1D). We use cloned T cell lines and TCR transgenic mice to study the disease process. Our goals are to acquire better understanding of how CD4 T cells contribute to pathogenesis in T1D, investigate the beta cell autoantigens that activate autoreactive T cells, and develop new strategies for inducton of tolerance and prevention of disease.

Education

Education
University of Kansas (Lawrence, KS), PhD, Biochemistry
Fellowship
National Jewish Health, Postdoctoral Fellowship in Immunology

Professional Memberships

AAI, American Diabetes Association, Immunology of Diabetes Society

Publications

Haskins, K. 2005. Pathogenic T cell clones in autoimmune diabetes: more lessons from the NOD mouse. Advances in Immunol. 87: 123-62.

Cantor, J. and Haskins, K. (2005) Effector Function of Diabetogenic CD4 Th1 T cell clones: A Central Role for TNFa. J. Immunol. 175: 7738-45.

Cantor, J. and Haskins, K. (2007) Recruitment and activation of macrophages by pathogenic CD4 T cells in T1D: Involvement of CCR8 and CCL1. J. Immunol. 179: 5760-67. Tonkin, D.R., He, J., Barbour, G. and Haskins, K. 2008. Regulatory T cells prevent transfer of type 1 diabetes in NOD mice only when their antigen is present in vivo. J. Immunol. 181: 4516-22

Tonkin, D.R. and Haskins, K. 2009. Regulatory T cells enter the pancreas during suppression of type 1 diabetes and inhibit effector T cells and macrophages in a TGF-ß-dependent manner. Eur. J. Immunol. 39: 1313-22.

Stadinski, B.D.*, Delong, T.*, Reisdorph, N., Reisdorph, R., Powell, R.L., Armstrong, M., Piganelli, J.D., Barbour, G., Bradley, B., Crawford, F., Marrack, P., Mahata, S.K., Kappler, J.W. and Haskins, K. 2010. Chromogranin A is an autoantigen in type 1 diabetes. Nature Immunology 11: 225-31.

*Denotes equal contributions.

Academic Affiliations

Professor, Department of Immunology, University of Colorado Denver

Contact Information

  • Office: 303.270.2093
  • Fax: 303.270.2325
  • Email: katie.haskins@ucdenver.edu

 

Locations

  • National Jewish Health Main Campus
    1400 Jackson St.
    Denver, CO 80206

Patient Ratings

The Patient Rating score is an average of all responses to care provider related questions on our independent rating system, the Press Ganey Patient Satisfaction Survey.

Responses are measured on a scale of 1 to 5, with 5 being the best score. Learn more about our patient satisfaction survey.
 
 

Comments

Comments are collected in our Press Ganey Patient Satisfaction Surveys. Patients are de-identified to protect confidentiality and patient privacy. Learn more about our patient satisfaction survey.