Gregory P. Downey
Professor
Executive Vice President, Academic Affairs
Department of Medicine
Division of Pulmonary, Critical Care and Sleep Medicine
  • 5280 Top Doctors 2016
  • Recognized as a 5280 Top Doctor
  • America’s Top Doctors 2015 — Castle Connolly, Medical, Ltd.
  • Recognized in America’s Top Doctors — Castle Connolly, Inc.
  • Best Doctors in America® 2015 — Best Doctors, Inc.
  • Recognized in Best Doctors in America® — Best Doctors, Inc.
  • America’s Top Doctors 2016 — Castle Connolly Medical, Ltd.
  • Specialties and ConditionsSpecialties & Conditions
    Research AreasResearch Areas
    • Basic Immunology
    • Cellular and Molecular Biology
    • Infectious Diseases
    • Inflammation

    Education

    Education
    University of Manitoba (Winnipeg, Canada), MD
    Residency
    Beth Israel Hospital, Harvard Medical School, Residency in Internal Medicine
    Beth Israel Hospital, Harvard Medical School, Internship in Internal Medicine
    Fellowship
    National Jewish Health and University of Colorado Denver, Research Fellowship in Pulmonary Cell Biology
    University of Colorado Denver, Clinical Fellowship in Pulmonary Medicine

    Awards & Recognition

    2010: American Thoracic Society Recognition Award for Scientific Accomplishments

    2002-Present: Assoc. Editor, American Journal of Respiratory Cell and Molecular Biology

    2006: Canadian Cystic Fibrosis Foundation Zeller’s Senior Scientist Award for outstanding contributions to CF Research

    2004: Scholar, McLaughlin Centre for Molecular Medicine, U. of Toronto

    2001: Tier 1 Canada Research Chair in Respiration, Canadian Institutes of Health Research

    1999: R. Fraser Elliott Chair in Transplantation Research, Toronto General Hospital, University Health Network

    1999: Dept. of Med. Research Award, U. of Toronto

    1997: Elected to the American Society for Clinical Investigation. Recipient of the William Goldie Prize, Dept. of Med., U. of Toronto for a contribution of notable merit to the advancement of knowledge in Internal Medicine

    1996: Institute of Medical Science, Dept. of Medicine, U. of Toronto. Special Recognition for Supervision of Graduate Students who have made a notable scientific contribution

    1992: Royal College of Physicians and Surgeons of Canada, Canadian Society of Clinical Investigation Joe Doupe Young Investigator’s Award

    1989: Career Scientist Award, Ontario Ministry of Health

    Board Certification

    National Board of Medical Examiners, Parts 1, 2 and 3

    American Board of Internal Medicine

    Fellow of the Royal College of Physicians and Surgeons of Canada Royal College of Physicians and Surgeons of Canada: Special Certificate in Respiratory Diseases

    American Board of Pulmonary Diseases

    Special Certification in Critical Care (American Board of Internal Medicine)

    Fellow of the American College of Chest Physicians

    Professional Memberships

    Royal College of Physicians and Surgeons of Canada, Full Member

    American Thoracic Society, Full Member; Member Program Committee for Assembly on Allergy, Immunology, and Inflammation, 1996-Present

    American College of Chest Physicians, Full Member

    Member of Forum on Critical Care

    American Society for Cell Biology, Full Member.

    Scientific Forum on Lung Cell and Molecular Biology

    American Association for the Advancement of Science, Full Member

    Ontario Thoracic Society, Full Member

    Federation of American Societies for Experimental Biology, Full Member

    Clinical Research Society or Toronto, President, 1996-1999

    Publications

    McCormack FX, Inoue Y, Moss J, Singer LG, Strange C, Nakata K, Barker AF,  Chapman JT,  Brantly ML, Stocks JM,  Brown KK,  Lynch JP, 3rd, Goldberg HL, Young LR, Kinder BM,  Downey GP, Sullivan ET, Colby TV, McKay RT,  Cohen MM,  Korbee L, Taveira-DaSilva AM, Lee H-S, Krischer JP, and Trapnell BC, for the NIH Rare Lung Diseases Consortium and the Multicenter International Lymphangioleiomyomatosis Efficacy and Safety of Sirolimus (MILES) Trial. Efficacy and Safety of Sirolimus in Lymphangioleiomyomatosis. N Eng J Med. 364;1595-1606, 2011. PMC3118601

    Yamashita C, Dolgonos L, Zemans RL, Young SK, Robertson J, Briones N, Suzuki T, Campbell MN, Gauldie J, Radisky DC, Riches DW, Yu G, Kaminski N, McCulloch CA, and GP Downey.  Matrix metalloproteinase-3 is a mediator of pulmonary fibrosis.  Am J Path 179:1733-45, 2011. PMC3181358.

    Zemans R, Briones N, Campbell M, McClendon J, Young SK, Suzuki T, Yang IV, de Langhe S, Reynolds SD, Mason RJ, Kahn M, Henson PM, Colgan SP, and GP Downey. Neutrophil transmigration triggers repair of the lung epithelium via β-catenin signaling.  Proc Nat Acad Sci (USA) 108:15990-15995, 2011. PMC3179042.

    Stallings-Mann ML, Waldmann J, Zhang Y, Miller E, Gauthier ML, Visscher DW, Downey GP, Radisky ES, Fields AP, and DP Radisky.  Matrix metalloproteinase induction of Rac1b, a key effector of lung cancer progression. Sci Transl Med 4(142):142ra95, 2012. PMC3733503.

    Zemans R, McClendon J, Aschner Y, Briones N, Young SK,. Lau LF, Kahn M, and GP Downey. Role of β-catenin-regulated CCN matricellular proteins in epithelial repair after inflammatory lung injury. Am J Physiol (Lung Cell Mol Physiol) 304: L415-27, 2013. PMC3602744.

    Hospital Affiliations

    • Hospital for Sick Children
    • Mt. Sinai Hospital
    • Toronto General Hospital

    Teaching & Professional Positions

    2007-Present: Professor, Dept of Pediatrics, National Jewish Health

    2007-Present: Professor, Integrated Department of Immunology, National Jewish Health & University of Colorado Denver

    2006-Present: Executive Vice President for Academic Affairs and Professor, Dept of Medicine, National Jewish Health

    2004-2006: Vice-Chair, Dept of Medicine, University of Toronto

    2001-2006: Canada Research Chair in Respiration, Canadian Institutes of Health Research

    2001-2006: Associate Director, Institute of Medical Sciences, University of Toronto 8/01-10/30/06

    2000-2006: Director, Division of Respirology, University of Toronto

    1999-2006: Professor, Dept of Medicine, University of Toronto

    1999-2005: R. Fraser Elliot Chair in Transplantation Research, Toronto General Hospital, The University Health Network

    1995-2000: Training Program Director, Division of Respirology, University of Toronto

    1993-2006: Full Member, School of Graduate Studies, University of Toronto

    1993-1999: Associate Professor, Dept of Medicine, University of Toronto

    1989-1993: Associate Member, School of Graduate Studies, University of Toronto

    1988-1993: Assistant Professor, Dept of Medicine, University of Toronto

    1987-1988: Assistant Professor, Dept of Medicine, University of Colorado Denver

    Conflicts of Interest

    National Jewish Health physicians and scientists may collaborate with pharmaceutical or other industries to develop medical and scientific breakthroughs or to provide education on trends in quality medical practice and outcomes to physicians and health professionals around the country. National Jewish Health maintains a strict conflict of interest policy to ensure that all potential conflicts are clearly visible and that management plans are put in place in order to further innovation and education while ensuring the protection of our patients and the integrity of our research. National Jewish Health publicly discloses any payment to our physicians or scientists. View this faculty member’s industry relationships and collaborations.

    Contact Information

    • Office: 877.225.5654
    • Fax: 303.270.2243
    • Email: DowneyG@njhealth.org

     

    Locations

    • National Jewish Health Main Campus
      1400 Jackson St.
      Denver, CO 80206

    Patient Ratings

    The Patient Rating score is an average of all responses to care provider related questions on our independent rating system, the Press Ganey Patient Satisfaction Survey.

    Responses are measured on a scale of 1 to 5, with 5 being the best score. Learn more about our patient satisfaction survey.
     

    Friendliness
    5

    Recommended to others
    5

    Explanation of problem/condition
    5

    Shows concerns for your questions
    5

    Includes you in decisions
    4.9

    Spoke using clear language
    5

    Amount of time spent with you
    5

    Confidence in your doctor
    5
     

    Comments

    Comments are collected in our Press Ganey Patient Satisfaction Surveys. Patients are de-identified to protect confidentiality and patient privacy. Learn more about our patient satisfaction survey.
     

    National Jewish Health PatientMay, 2016
    I only see Downey. All good!