The Centers for Disease Control and Prevention (CDC) recommends that NAAT should be performed on at least one respiratory specimen from each patient with signs and symptoms of pulmonary TB for whom a diagnosis of TB is being considered but has not yet been established, and for whom the test result would alter case management or TB control activities.
TB NAAT is not performed on swabs, stool, or blood specimens.
Typically all days.
Real-time PCR or line probe assay
Results are typically reported in less than a day, but may be 1-3 days for non sputum sources.
Infectious Disease Laboratory, Mycobacteriology
Mycobacterial PCR, Tuberculosis PCR , MDR, TB PCR, MTB PCR
This test is a component of AFB1; MTB4 is a genotypic assay to detect resistance markers to first line drugs.
Sputum: FDA approved. Validated LDT for other sources (see Method in Collection Requirements).
Non-sputum sources: NYS waiver required for samples sent from NYS.
M. tuberculosis complex not detected.