Draw one green top tube (Sodium or Lithium Heparin), or one lavender top tube (EDTA).
Do not centrifuge! Keep at room temp (18-22°C).
Preferred volume: 4 mL
Minimum volume: 1 mL blood
Frozen, clotted, hemolyzed or centrifuged specimens. Anticoagulants other than heparin or EDTA. Specimens >24 hrs old.
Maintain and transport specimens at room temperature (18-22°C).
Ship specimens Priority Overnight via Fed Ex in container sufficiently insulated to avoid temperature extremes (<10°C and >37°C).
24 hours at room temperature (18-22°C)
Samples must arrive within 24 hours of draw and are accepted Monday through noon on Friday.
Immunology Lab - Phenotyping Assays
Membrane Co-factor Protein (CD46), MCP (CD46), CD46, Membrane, Cofactor
CD46 is expressed on WBCs of normal individuals.
Mutations of genes encoding Factors H and I and the membrane cofactor (MCP or CD46) are associated with atypical hemolytic uremic syndrome AHUS). Decreased expression of CD46 may be associated with atypical HUS.