Industry-Sponsored Research Partnerships

Personalized medicine is the backbone of the National Jewish Health Chronic Obstructive Pulmonary Disease (COPD) Program incorporating:

  • Advanced diagnostics for early detection and risk assessment
  • Individualized therapy with a multidisciplinary approach
  • Industry-sponsored and NIH-funded research by our nationally renowned experts

As one of the largest pulmonary disease referral centers in the world, we have access to thousands of COPD patients, biological samples and animal models that can lead to new discoveries in genotyping, pharmacology, and treatments that optimize each patient’s COPD care and quality of life.

Rohit K. Katial

Rohit K. Katial, MD

Russell P. Bowler

Russell P. Bowler, MD, PhD

Gary R. Cott

Gary R. Cott, MD

James D. Crapo

James D. Crapo, MD

Barry J. Make

Barry J. Make, MD

Richard J. Martin

Richard J. Martin, MD

Robert J. Mason

Robert J. Mason, MD

Robert A. Sandhaus

Robert A. Sandhaus, MD, PhD, FCCP

David A. Beuther

David A. Beuther, MD

William J. Janssen

William J. Janssen, MD

James T. Good Jr

James T. Good Jr, MD

Gregory P. Downey

Gregory P. Downey, MD

Donald R. Rollins

Donald R. Rollins, MD

Elaine M K Schwartz

Elaine M K Schwartz, MD, FCCP

Michelle A. Beutz

Michelle A. Beutz, MD

James J. Fenton

James J. Fenton, MD

Robert M. Maulitz

Robert M. Maulitz, MD

Richard D. Mountain

Richard D. Mountain, MD, FCCP

David A. Taryle

David A. Taryle, MD, FCCP

Susan Kotake

Susan Kotake, MD

William T. Pluss

William T. Pluss, MD, FCCP

Michael D. Schwartz

Michael D. Schwartz, MD, FACP, FCCM, FCCP

Sheila Tsai

Sheila Tsai, MD

Vipin Malik

Vipin Malik, MD

Jennifer Wink

Jennifer Wink, MD

Ahmad M. Rashid

Ahmad M. Rashid, MD, FCCP

Anthony N. Gerber

Anthony N. Gerber, MD, PhD

Michelle MacDonald

Michelle MacDonald, MS, RDN, CDE

Bronwyn Long

Bronwyn Long, DNP, MBA, RN

James H. Finigan

James H. Finigan, MD

Steven E. Lommatzsch

Steven E. Lommatzsch, MD

Peter C. Stubenrauch

Peter C. Stubenrauch, MD

Zulma X. Yunt

Zulma X. Yunt, MD

Robert N. Glidewell

Robert N. Glidewell, PsyD

Michael E. Wechsler

Michael E. Wechsler, MD, MMSc

Anita Trikha

Anita Trikha, MD

Shelby R. Jenkins

Shelby R. Jenkins, OTR

Robert J. Lapidus

Robert J. Lapidus, MD

Jason D. McCarl

Jason D. McCarl, MD

James K. O

James K. O'Brien, MD, FACP, FCCP

Amen Sergew

Amen Sergew, MD

James Woodrow

James Woodrow, MD

Laurie A. Manka

Laurie A. Manka, MD

Matthew D. Cohn

Matthew D. Cohn, MD

Evan L. Stepp

Evan L. Stepp, MD

Irina Petrache

Irina Petrache, MD

Karina A. Serban

Karina A. Serban, MD

Dionne M. Morgan

Dionne M. Morgan, MD

Chelsea M. Randall

Chelsea M. Randall, MS, OTR/L

Brittany A. Harris

Brittany A. Harris, BS

Kasia Hoover

Kasia Hoover, PA-C

Clara Restrepo

Clara Restrepo, MD

Akrum Al-Zubaidi

Akrum Al-Zubaidi, DO

Anuj Mehta

Anuj Mehta, MD

Howard Saft

Howard Saft, MD, MS

Katherine Rosen

Katherine Rosen, RN, MSN, ANP-C

Jennifer Sederberg

Jennifer Sederberg, NP

Janice Herrell

Janice Herrell, NP

Marjorie Patricia George

Marjorie Patricia George, MD

Ann Granchelli

Ann Granchelli, MD

Catherine Wittman

Catherine Wittman, MD

Jacob Beans

Jacob Beans, MSN, NP-C

Ted McMenomy

Ted McMenomy, MD

Therese Ida

Therese Ida, MS, RDN

Clinical COPD Program

The National Jewish Health COPD Program offers multidisciplinary, comprehensive, personalized care for people with chronic obstructive pulmonary disease (COPD), including emphysema and chronic bronchitis.

As the region's only full-service COPD program, our clinicians see 3,000 patients each year with the goal to help them manage their disease effectively, and live full and active lives.
 

COPD Research

COPD research at National Jewish Health is made possible through funding from a wide variety of sources such as the National Institutes of Health, the National Heart, Lung and Blood InstituteMedicare, foundations and industry sponsors.

COPD Scientific Discoveries at National Jewish Health

  • Interplay of genes and environment
  • Efficacy of pharmacological treatments
  • Cellular changes from smoking
  • Long-term drug safety

COPD Clinical Research Areas of Interest

  • Pharmacological treatments
  • Psychosocial aspects of disease management
  • Quality of life factors
  • Screening tool development
  • Environmental factors
  • Genetic factors

COPD Biorepository

National Jewish Health has a repository of biological specimens from more than 4,000 COPD patients seen at National Jewish Health. By cross-referencing these samples with our electronic medical record (EMR), we are able to identify highly relevant samples derived from clinical information collected over time, including laboratory testing, symptoms, diagnoses and demographics.

COPD Basic Research

Investigators at National Jewish Health conduct extensive basic research into the mechanisms involved in the development and resolution of emphysema and chronic bronchitis.

COPD Basic Research Areas of Interest

  • Translational studies of COPD development mechanisms 
  • COPD genetic association studies
  • GWAS for airflow limitation and emphysema
  • COPD genomic studies
  • Proteomics studies of COPD
  • Metabolomic studies of COPD
  • Biomarkers predictive of acute exacerbations and hospitalizations for COPD
  • Novel drug therapy to reduce progression of COPD

COPD Animal Models

National Jewish investigators use several animal models to study aspects of the development and resolution of COPD based on well-characterized experimental endpoints that include airway inflammation and emphysema.

  • Mouse tobacco smoke exposure model
  • Rat tobacco smoke exposure model
  • E-cigarette mouse exposure models
  • Morphometric analysis of lung
  • Genomics of lung disease
  • Metabolomics of lung disease
  • Proteomics of lung disease
  • Systems biology with insights into COPD pathogenesis

COPD Cell Cultures

National Jewish investigators also have extensive expertise in the in vitro study of tobacco smoke. These studies involved assessment of exposure of either whole tobacco smoke or cigarette smoke extract. An extensive collection of primary peripheral blood and airway cells as well as banked lung tissue are available from COPD patients.