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In the United States asthma has reached epidemic proportions:

  • one in 12 adults and one in 11 children have asthma
  • nine people die every day from the disease

Asthma treatment at National Jewish Health helps address this health problem using a multidisciplinary and multispecialty care approach that integrates clinical and research efforts to deliver the best care possible and expedite the bench-to-bedside process resulting in successful asthma care, management and research.

We are dedicated to gaining a better understanding of asthma with the ultimate goal of discovering novel therapeutic options for patients with this challenging disease.

As one of the largest asthma specialty care centers in the world, we have nearly 30,000 patient visits annually, a varied asthma patient population, and a multitude of ongoing asthma research endeavors.

Rohit K. Katial

Rohit K. Katial, MD

Rafeul Alam

Rafeul Alam, MD, PhD

Richard J. Martin

Richard J. Martin, MD

David A. Beuther

David A. Beuther, MD, PhD, FCCP

Gregory P. Downey

Gregory P. Downey, MD

Elaine M K Schwartz

Elaine M K Schwartz, MD, FCCP

Michael D. Schwartz

Michael D. Schwartz, MD, FCCM

Sheila Tsai

Sheila Tsai, MD

Vipin Malik

Vipin Malik, MD

Anthony N. Gerber

Anthony N. Gerber, MD, PhD

Steven E. Lommatzsch

Steven E. Lommatzsch, MD

Flavia Cecilia Lega Hoyte

Flavia Cecilia Lega Hoyte, MD

Michael E. Wechsler

Michael E. Wechsler, MD, MMSc

Shelby R. Jenkins

Shelby R. Jenkins, OTR

James K. O

James K. O'Brien, MD, FACP, FCCP

James Woodrow

James Woodrow, MD

Laurie A. Manka

Laurie A. Manka, MD

Kanao Otsu

Kanao Otsu, MD, MPH

Evan L. Stepp

Evan L. Stepp, MD

Irina Petrache

Irina Petrache, MD

Howard Saft

Howard Saft, MD, MS

Katherine Rosen

Katherine Rosen, RN, MSN, ANP-C

Jennifer Sederberg

Jennifer Sederberg, NP

Marjorie Patricia George

Marjorie Patricia George, MD

Eileen Wang

Eileen Wang, MD, MPH

Ann Granchelli

Ann Granchelli, MD

Ron Balkissoon

Ron Balkissoon, MD, MSc, DIH, FRCPC

Claudia Onofrei

Claudia Onofrei, MD, MSc

Vamsi P. Guntur

Vamsi P. Guntur, MD, MSc

Gabriel C. Lockhart

Gabriel C. Lockhart, MD

David M. Ferraro

David M. Ferraro, MD

Matthew Koslow

Matthew Koslow, MD

Hilda Metjian

Hilda Metjian, MD, FCCP

Allison Zangle

Allison Zangle, PT, DPT (1)

Elizabeth K. George

Elizabeth K. George, MD, MPH

Jessica Galant-Swafford

Jessica Galant-Swafford, MD

Christine Nguyen

Christine Nguyen, DO

Sean Maddock

Sean Maddock, MD

Anne DelBovo

Anne DelBovo, NP

Savannah Shannon

Savannah Shannon, PA-C

Yakira Gruber

Yakira Gruber, DPT (1)

Adriel J. Malavé

Adriel J. Malavé, MD

Ryan Webster

Ryan Webster, MD

Jordan Bull

Jordan Bull, PA-C

Megan Baumgardner

Megan Baumgardner, PT, DPT (1)

Michael Nevid

Michael Nevid, MD

Clinical Asthma Program

As one of the nation’s top respiratory centers, National Jewish Health treats more than 7,500 asthma patients annually and offer the most comprehensive and individualized range of treatment programs available for patients annually with mild to severe asthma. We utilize a multidisciplinary approach, tailored diagnostics and therapeutics, patient education and psychological treatment to help patients gain control over their disease and dramatically improve their quality of life.
 
Learn more about our Adult Asthma Program Learn more about our Pediatric Asthma Program  

Clinical Asthma Research

Asthma research at National Jewish Health is made possible through funding from a wide variety of sources such as the National Institutes of Health, the National Heart, Lung and Blood Institute (NHLBI), Medicare, industry sponsors and private donors.

Our investigators are part of the NHLBI’s Asthma Clinical Research Network (Asthmanet), the American Lung Association Clinical Research Consortium and are leaders in asthma clinical trials.

Asthma Scientific Discoveries at National Jewish Health

  • IgE, the molecule - this discovery has become the basis for many new treatments for asthma and allergies.
  • Mechanisms of apoptosis - pioneering efforts led us to understand how the body effectively removes and recycles up to two billion cells a day and resolves inflammation in the lung.
  • Immune response trigger - research revealed that fragments of proteins from invading organisms bound to and presented by MHC molecules triggers the adaptive immune response.
  • The immunological synapse – our scientists found the complex and long-lived connection between immune-system cells that greatly influences the immune response.
  • New family of anti-viral agents – research proved that a naturally occurring lipid fights viral infections and related inflammation in the lungs.

Asthma Clinical Research Areas of Interest

  • Development of novel therapies and biologics for asthma
  • Molecular, cellular and animal model approaches to understand the mechanism of asthma
  • Psychosocial aspects of disease management
  • Quality of life factors
  • Accurate diagnostic tool development
  • Environmental factors
  • Genetic factors

Asthma Biorepository

National Jewish Health developed an asthma biorepository that includes nearly 2,000 adult patient biological and tissue samples tied to phenotypic information that can lead to new discoveries in genotyping, pharmacology, and treatments that optimize each patient’s asthma care and quality of life.

Asthma Basic Science

Asthma researchers at National Jewish Health conduct important basic science research that has improved our understanding of the underlying biologic causes of asthma. Importantly, NJH researchers are utilizing this research to translate findings into humans.

Asthma Translational Research Resources

  • Novel human lung cell systems
  • Genetic animal models of pulmonary disease
  • Animal pulmonary physiology
  • Animal inhalation exposure systems
  • Active drug development program
  • Asthma Pharmacogenetics

Asthma Animal Models and Cell Cultures

National Jewish Health investigators use several animal models and an extensive collection of cell cultures available from patients with asthma to study aspects of the underlying mechanisms of asthma development and to gain insight into systems biology and into asthma pathogenesis.