Max Seibold, PhD Ask a Question Refer Patient Max Seibold, PhD, is a researcher at National Jewish Health. Dr. Seibold is in the Center for Genes, Environment & Health and Office of Academic Affairs. Professor Director, Regenerative Medicine and Genome Editing Program (REGEN) Center for Genes, Environment & Health Department of Pediatrics Office of Academic Affairs 5280 Top Doctors 2022 Previously a 5280 Top Doctor America’s Top Doctors 2015 — Castle Connolly, Medical, Ltd. Recognized in America’s Top Doctors — Castle Connolly, Inc. Best Doctors in America® 2019-2020 — Best Doctors, Inc. Recognized in Best Doctors in America® — Best Doctors, Inc. America’s Top Doctors 2020 — Castle Connolly Medical, Ltd. Email Profile Print Profile Overview Contact Info & Locations Programs & Services Center for Genes, Environment and Health Research Areas Epidemiology Genetics Genomics Molecular Genetics Pulmonary Fibrosis Asthma Special Interests The Seibold Lab is focused on identifying genetic determinants and biomarkers of complex lung diseases, including asthma and pulmonary fibrosis. Many of the genetic variants that influence development and severity of these lung diseases do so by altering molecular functions in specific lung cell types. His lab is focused on identifying dysregulated molecular functions in patient lung cells, by Nex-Generation sequencing technologies. Using patient cohorts the genetic determinants of these molecular changes are then mapped. The lab is also editing the genome of these lung cells to allow detailed mechanistic studies of disease variants and better understanding of how these genetic changes increase risk of disease development. News & Videos National Jewish Health Awarded $11.5 Million in Department of Defense Grants Researchers to Study Drivers of Asthma in Puerto Rico 'Silent' Viral Infections Promote Profound Biological Response Study Finds that Genetic Risk for Asthma Comes from Changes in Airway Cells The Nose Knows in Asthma Education Education 2008 - 2011 National Jewish Health, Genetics of Pulmonary Fibrosis, Laboratory of Dr. David Schwartz 2008 University of California-San Francisco, PhD, Pharmaceutical Sciences and Pharmacogenomics 2001 Southwestern Oklahoma State University, Chemistry Publications A common MUC5B promoter polymorphism and pulmonary fibrosis. Seibold MA, Wise AL, Speer MC, Steele MP, Brown KK, Loyd JE, Fingerlin TE, Zhang W, Gudmundsson G, Groshong SD, Evans CM, Garantziotis S, Adler KB, Dickey BF, du Bois RM, Yang IV, Herron A, Kervitsky D, Talbert JL, Markin C, Park J, Crews AL, Slifer SH, Auerbach S, Roy MG, Lin J, Hennessy CE, Schwarz MI, Schwartz DA. N Engl J Med. 2011 Apr 21;364(16):1503-12. Genetic ancestry in lung-function predictions. *Kumar R, *Seibold MA, *Aldrich MC, *Williams LK, Reiner AP, Colangelo L, Galanter J, Gignoux C, Hu D, Sen S, Choudhry S, Peterson EL, Rodriguez-Santana J, Rodriguez-Cintron W, Nalls MA, Leak TS, O'Meara E, Meibohm B, Kritchevsky SB, Li R, Harris TB, Nickerson DA, Fornage M, Enright P, Ziv E, Smith LJ, Liu K, Burchard EG.N Engl J Med. 2010 Jul 22;363(4):321-30. Epub 2010 Jul 7. Differential enzymatic activity of common haplotypic versions of the human acidic Mammalian chitinase protein. Seibold MA, Reese TA, Choudhry S, Salam MT, Beckman K, Eng C, Atakilit A, Meade K, Lenoir M, Watson HG, Thyne S, Kumar R, Weiss KB, Grammer LC, Avila P, Schleimer RP, Fahy JV, Rodriguez-Santana J, Rodriguez-Cintron W, Boot RG, Sheppard D, Gilliland FD, Locksley RM, Burchard EG. J Biol Chem. 2009 Jul 17;284(29):19650-8. Epub 2009 May 12. Chitotriosidase is the primary active chitinase in the human lung and is modulated by genotype and smoking habit. Seibold MA, Donnelly S, Solon M, Innes A, Woodruff PG, Boot RG, Burchard EG, Fahy JV. J Allergy Clin Immunol. 2008 Nov;122(5):944-950.e3. Epub 2008 Oct 9. Teaching & Professional Positions 2015-present Associate Professor, CGEH, Department of Pediatrics, National Jewish Health 2011-2015 Assistant Professor, CGEH, Department of Pediatrics, National Jewish Health Ask a Question through Patient Portal Sign in to your My National Jewish Health patient portal account to communicate with your care team, manage appointments, and more. Create an Account Contact Information Office: 877.225.5654 Locations National Jewish Health Main Campus 1400 Jackson St. Denver, CO 80206 Patient Ratings The Patient Rating score is an average of all responses to care provider related questions on our independent rating system, the Press Ganey Patient Satisfaction Survey. 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