Magdalena Maria Gorska, MD, PhD

Magdalena Maria Gorska
Magdalena Maria Gorska, MD, is a researcher at National Jewish Health. Dr. Gorska is in the Division of Allergy and Clinical Immunology.
Associate Professor
Department of Biomedical Research
Department of Medicine
Division of Allergy & Clinical Immunology

Special Interests

Research Interests

Our laboratory studies the early life origins of asthma. A proportion of patients with asthma develops symptoms of their disease very early in life, sometimes in its first year. Genetic factors are contributory but fail to fully explain it. It is therefore increasingly recognized that development of early-life asthma is driven in substantial part by environmental exposures that are encountered by infants after birth and, indirectly, by exposures encountered by their mothers, in association with pregnancy and breastfeeding. Our laboratory is focused on maternal exposures, trying to delineate how they lead to asthma in offspring. The goals are to define maternal information that is gained and transmitted to offspring or lost and not transferred to offspring, elucidate routes of information transfer (placenta, breast milk, gametes), and delineate cells and pathways that are affected in offspring (cells and molecules of the immune system are of particular interest). The translational goals are to identify early-life biomarkers of predisposition to asthma in humans and define molecular targets for development of preventive drugs.  To accomplish these goals, the laboratory uses mouse models, blood samples from young children with high risk of developing asthma (API+), and a variety of immunological, signaling, transcriptomics and epigenetic approaches.

Education

Education
Medical University of Lodz, Poland, Habilitation degree
Medical University of Lodz, Poland, PhD
Medical University of Lodz, Poland, MD
Fellowship
National Jewish Health, Denver, CO, Postdoctoral Fellowship
University of Texas Medical Branch, Galveston, TX, Postdoctoral Fellowship

Awards & Recognition

2015-2019: 1R01HL122995-01A1
2015: National Jewish Health Outstanding Scientific Achievement Award
2014-2015: Biomedical Research Grant, American Lung Association
2012-2013: Faculty Development Investigator Award, Denver Children’s Environmental Health Center (NIEHS PO1 ES-018181 and EPA GAD 834515010)
2012: Invited speaker, Presidential Plenary Session, Annual Meeting of the American Academy of Asthma, Allergy and Immunology
2011-2014: KL2 Research Scholar Award, Colorado Clinical and Translational Sciences (NIH, KL2 TR001080)
2011-2013: Sheldon C. Siegel Investigator Grant Award, Asthma and Allergy Foundation of America
2011: Pilot grant, Basic Science Section of the Department of Medicine at National Jewish Health
2010-2011: Junior Faculty Pilot Award, Colorado Clinical and Translational Sciences Institute (NIH, UL1 TR001082)
2009: Invited speaker, Annual Meeting of the European Academy of Allergy and Clinical Immunology
2005-2006: Interest Section Award, American Academy of Asthma, Allergy and Immunology
2000-2002: James W. McLaughlin Award, University of Texas
1998-1999: Ministry of Health Scholarship, Poland
1996: European Union Tempus Scholarship, Nijmegen University Hospital, Holland
1993-1998: Lodz Medical University Scholarship, Poland
1992-1993: Polish Children Fund Scholarship, Poland
 

Professional Memberships

American Academy of Asthma, Allergy, and Immunology
American Association of Immunologists
Collegium Internationale Allergologicum

 

Publications

Verma M, Liu S, Michalec L, Sripada A, Gorska MM, Alam R.   Experimental asthma persists in IL-33 receptor knockout mice because of the emergence of thymic stromal lymphopoietin-driven IL-9+ and IL-13+ type 2 innate lymphoid cell subpopulations.  J Allergy Clin Immunol. 2018 Sep;142(3):793-803.e8.

Lenberg J, Qian Q, Sun Z, Alam R, Gorska MM.  Pre-pregnancy exposure to diesel exhaust predisposes offspring to asthma through IL-1β and IL-17A. J Allergy Clin Immunol. 2018 Mar;141(3):1118-1122.e3.

Liu S, Verma M, Michalec L, Liu W, Sripada A, Rollins D, Good J, Ito Y, Chu H, Gorska MM, Martin RJ, Alam R.  Steroid resistance of airway type 2 innate lymphoid cells from patients with severe asthma: The role of thymic stromal lymphopoietin.  J Allergy Clin Immunol. 2018 Jan;141(1):257-268.e6.

Academic Affiliations

Associate Professor, Department of Medicine, Division of Allergy and Clinical Immunology, National Jewish Health

Teaching & Professional Positions

Associate Professor, Department of Medicine, Division of Allergy and Clinical Immunology, National Jewish Health

Conflicts of Interest

National Jewish Health physicians and scientists may collaborate with pharmaceutical or other industries to develop medical and scientific breakthroughs or to provide education on trends in quality medical practice and outcomes to physicians and health professionals around the country. National Jewish Health maintains a strict conflict of interest policy to ensure that all potential conflicts are clearly visible and that management plans are put in place in order to further innovation and education while ensuring the protection of our patients and the integrity of our research. National Jewish Health publicly discloses any payment to our physicians or scientists. View this faculty member’s industry relationships and collaborations.

Ask a Question through Patient Portal

Sign in to your My National Jewish Health patient portal account to communicate with your care team, manage appointments, and more. Create an Account
 

Contact Information

  • Office: 877.225.5654

 

Locations

  • National Jewish Health Main Campus
    1400 Jackson St.
    Denver, CO 80206

Patient Ratings

The Patient Rating score is an average of all responses to care provider related questions on our independent rating system, the Press Ganey Patient Satisfaction Survey. This survey is about the patient care experience and does not address crucial characteristics like medical decision-making, prescribing the best therapy, and patient outcomes.

Responses are measured on a scale of 1 to 5, with 5 being the best score. Learn more about our patient satisfaction survey.
 
 

Comments

Comments are collected in our Press Ganey Patient Satisfaction Surveys. Patients are de-identified to protect confidentiality and patient privacy. Learn more about our patient satisfaction survey.