John C. Cambier, PhD

John C. Cambier
Department of Biomedical Research
John C. Cambier, PhD, is a researcher at National Jewish Health. Dr. Cambier is in the Department of Biomedical Research.

Research AreasResearch Areas

Special Interests

Research Interests

Autoimmunity, immunodeficiency, allergy Transmembrane signal transduction in immune adaptation to environment queues and pathogens. Immunologic tolerance, regulation of the immune response and immunosenescence.


University of Iowa, PhD
University of Iowa, MS
SW Missouri State, BS
University of Texas, Southwestern Health Sciences Center,

Awards & Recognition

Ida and Cecil Green Chair

ISI Most Highly Cited

Editorial Boards: Immunity, Immunology, Immunologic Reviews, J. Clinical Immunology, BMC Immunology, Current Opinion in Immunology

Professional Memberships

American Association of Immunology


Decote-Ricardo D, Chagas KKF, Rocha JDB, Lima MEF, Redner P, Lopes UG, Cambier JC, Arruda-Hinds, L, Pecanha LMT. 2009. Modulation of in vitro murine B-lymphocyte response by curcumin and its synthetic analogues. Phytomedicine Oct; 16(10):982-8. PMID: 19303754

O’Neill S, Veselits M, Zhang M, Labno C, Cao Y, Finnegan A, Uccellini M, Alegre M, Cambier JC, Clark M. 2009. Endocytic sequestration of the B Cell Antigen Receptor and Toll-like Receptor 9 in Anergic Cells. Proc Natl Acad Sci U.S.A Apr 14;106(15):6262-7. PMID: 19332776

Jackson L, Cady CT , Cambier JC. 2009. TLR4-mediated signaling induces MMP9-dependent cleavage of B cell surface CD23. J Immunol Aug 15; 183(4):2585-92. PMID: 19635918

Getahun A, O’Neill SK, Cambier JC. 2009. Establishing anergy as a bona fide in vivo mechanism of B cell tolerance. J Immunol. Nov 1;183(9):5439-41. PMID: 19843930

Cady CT, Powell MS, Harbeck RJ, Giclas PC, Murphy JR, Katial RK, Weber RW, Hogarth PM, Johnson S, Bonvini E, Koenig S, Cambier JC. 2009. IgG antibodies produced during subcutaneous allergen immunotherapy mediate inhibition of basophil activation via a mechanism involving both Fc(gamma)RIIA and Fc(gamma)RIIB. Immunol Lett. Dec 14. PMID: 20004689

Academic Affiliations

Professor and Chair, Department of Immunology and Microbiology, University of Colorado School of Medicine

Teaching & Professional Positions

No current positions.


Industry Relationships & Collaborations

National Jewish Health physicians and scientists may collaborate with pharmaceutical or other industries to develop medical and scientific breakthroughs or to provide education on trends in quality medical practice and outcomes to physicians and health professionals around the country. National Jewish Health maintains a strict conflict of interest policy to ensure that all potential conflicts are clearly visible and that management plans are put in place in order to further innovation and education while ensuring the protection of our patients and the integrity of our research. National Jewish Health publicly discloses any payment to our physicians or scientists. View this faculty member’s industry relationships and collaborations.

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