Johanna K. DiStefano, PhD

Johanna K. DiStefano
Center for Genes, Environment & Health
Department of Biomedical Research
Johanna K. DiStefano, PhD, is a researcher at National Jewish Health. Dr. DiStefano is in the Center for Genes, Environment & Health.

Research AreasResearch Areas
  • Epigenetics
  • Liver Fibrosis
  • Pulmonary Fibrosis

Special Interests

I apply precision medicine approaches aimed at methods for early and noninvasive diagnostic assays, individualized treatment strategies in the clinical management of disease, and identification of targets for the development of new and improved therapeutics. My research program is designed to achieve an enhanced mechanistic understanding of complex disease processes, with a primary focus on fibrosis across all organs. We work with patient populations using state-of-the-art laboratory approache, including high throughput sequencing of DNA, RNA, and noncoding RNA,  in vitro model systems, functional genomics, and global DNA methylation analysis, to address important gaps in our understanding of disease pathogenesis and directly impact unmet clinical needs. 

Specialties: Genetics,  epigenetics, genomics, functional validation, drug discovery, new targets, biomarkers


Kent State University, PhD
National Institutes of Health, Fellowship

Professional Memberships

American Diabetes Association, American Society of Human Genetics, American Association for the Study of Liver Diseases

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Contact Information

  • Office: 303.270.2357
  • Email:



  • National Jewish Health Main Campus
    1400 Jackson St.
    Denver, CO 80206

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