James P. Bridges, PhD

James P. Bridges
James P. Bridges, PhD, is a researcher at National Jewish Health. Dr. Bridges is in the Division of Pulmonary, Critical Care and Sleep Medicine.
Associate Professor
Division of Pulmonary, Critical Care & Sleep Medicine
Department of Medicine
Research AreasResearch Areas
  • Alveolar Epithelial Cell Biology
  • Childhood Interstitial Lung Disease
  • Lung Development
  • Pulmonary Surfactant Homeostasis

Special Interests

Research efforts in the Bridges laboratory are focused toward: 1) understanding the molecular regulation of epithelial cell specification and maturation during lung development; and 2) determining the molecular mechanisms that control pulmonary surfactant pool sizes in the postnatal and adult lung, with particular interest in rare pediatric and adult lung diseases associated with surfactant dysfunction. Our lab utilizes state-of-the-art methodologies including CRISPR/Cas9 gene editing in mice, AAV-mediated gene delivery, RNAseq, ATACseq and high content confocal microscopy coupled with physiological and biochemical analyses to address questions of direct clinical relevance.

Education

Education
University of Cincinnati, Molecular and Developmental Biology, PhD
University of Colorado at Boulder, Biochemistry, BS
Fellowship
Cincinnati Children's Hospital, Pulmonary Biology

Website Information

Bridges Laboratory

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Contact Information

  • Office: 303.398.1792
  • Email: BridgesJ@NJHealth.org

 

Locations

  • National Jewish Health Main Campus
    1400 Jackson St.
    Denver, CO 80206

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