Elizabeth F. Redente, PhD Ask a Question Refer Patient Elizabeth F. Redente, PhD, is a researcher at National Jewish Health. Dr. Redente is in the Division of Cell Biology and Department of Pediatrics. Associate Professor Department of Pediatrics Division of Cell Biology 5280 Top Doctors 2021 Previously a 5280 Top Doctor America’s Top Doctors 2015 — Castle Connolly, Medical, Ltd. Recognized in America’s Top Doctors — Castle Connolly, Inc. Best Doctors in America® 2019-2020 — Best Doctors, Inc. Recognized in Best Doctors in America® — Best Doctors, Inc. America’s Top Doctors 2020 — Castle Connolly Medical, Ltd. Email Profile Print Profile Overview Contact Info & Locations Programs & Services Cell Biology Specialties & Conditions Interstitial Lung Disease (ILD)/Pulmonary Fibrosis Research Areas Fibroblast biology Interstitial Lung Disease (ILD) Macrophage Biology Pulmonary Fibrosis Special Interests My career interests are focused on the interactions between TNF-α, macrophages and myofibroblasts and their role in the resolution of established pulmonary fibrosis with the goal to investigate the mechanisms by which TNF-α resolves fibrosis as the basis for the translational application of this work as a potential therapeutic. We plan to elucidate the mechanisms by which TNF-α is reducing the pro-fibrotic phenotype of macrophages and myofibroblasts and via the creation of an anti-fibrotic lung microenvironment. The importance of understanding how macrophages are shaping the lung environment during disease and how these interactions can be modulated to influence disease resolution is an important research direction that can be applied to many diseases including fibrosis and cancer. It is my goal that my basic science findings conducted in mouse models be translatable to human disease and into potential therapeutic treatments. See More View Publications News & Videos ‘Beneficial inflammation’ May Promote Healing in Pulmonary Fibrosis ATS Foundation Awards Elizabeth Redente, PhD $40,000 to Investigate Medical Therapies for Pulmonary Elizabeth Redente Honored for Scientific Achievement Education Education University of Colorado Denver, PhD Publications Redente EF,Jacobsen KM, Solomon J, Lara A, Faubel S, Keith RC, Henson P, Downey GP, Riches DWH. 2011. Age and gender dimorphisms contribute to the severity of bleomycin-induced lung injury and fibrosis. Am J Physiol (LCMP) 301(4):L510-8.PMID: 21743030 Redente EF, Keith RC, Janssen WJ, Ortiz LA, Downey GP, Bratton DL, Riches DWH. 2014. TNF-aaccelerates the resolution of pulmonary fibrosis in mice by reprogramming lung macrophages. Am J of Respir Cell and Mol Biol. 50(4):825-837. PMID: 24325577 Redente EF, Aguilar MA, Black BP, Edelman BL, Bahadur A, Humphries SM, Lynch DA, Wollin SL, Riches DWH. Evaluation of therapeutic efficacy of nintedanib in a model of rheumatoid arthritis-associated interstitial lung disease. Am J Physiol Lung Cell Mol Physiol. 2018. Jun 1;314(6):L998-L1009. PMID: 29543042 Bamberg A*, Redente EF*, Groshong SD, Tuder RM, Cool CD, Keith RC, Edelman BL, Black BP, Cosgrove GP, Wynes MW, Curran-Everett D, De Lang S, Ortiz LA, Thorburn A, Grusby MJ, Riches DWH. The protein tyrosine phosphatase PTPN13 links lung fibroblast resistance to apoptosis with the development of pulmonary fibrosis. Am J Resp and Crit Care Med. 2018. Oct 1;198(7):914-927. PMID: 29727583 Tighe RM, Redente EF, Yu YR, Herold S, Sperling AI, Curtis JL, Duggan R, Swaminathan S, Nakano H, Zacharias WJ, Janssen WJ, Freeman CM, Brinkman RR, Singer BD, Jakubzick CV, Misharin AV. Improving the Quality and Reproducibility of Flow Cytometry in the Lung. An Official American Thoracic Society Workshop Report.Am J Respir Cell Mol Biol. 2019 Aug;61(2):150-161. PMID:31368812 Academic Affiliations Associate Professor of the University of Colorado School of Medicine, Department of Medicine, Division of Pulmonary Sciences and Critical Care Medicine Ask a Question through Patient Portal Sign in to your My National Jewish Health patient portal account to communicate with your care team, manage appointments, and more. Create an Account Contact Information Office: 303.398.1548 Email: RedenteE@njhealth.org Locations National Jewish Health Main Campus 1400 Jackson St. Denver, CO 80206 Patient Ratings The Patient Rating score is an average of all responses to care provider related questions on our independent rating system, the Press Ganey Patient Satisfaction Survey. This survey is about the patient care experience and does not address crucial characteristics like medical decision-making, prescribing the best therapy, and patient outcomes. Responses are measured on a scale of 1 to 5, with 5 being the best score. Learn more about our patient satisfaction survey. Comments Comments are collected in our Press Ganey Patient Satisfaction Surveys. Patients are de-identified to protect confidentiality and patient privacy. Learn more about our patient satisfaction survey.