Brian Vestal, PhD

Brian Vestal
Brian Vestal, PhD, is a researcher at National Jewish Health. Dr. Vestal is in the Center of Genes, Environment & Health and the Department of Immunology and Genomic Medicine.
Assistant Professor
Center for Genes, Environment & Health
Department of Immunology and Genomic Medicine
Research AreasResearch Areas
  • Bayesian Hierarchical Models
  • CT Scan Image Analysis
  • Generalized Linear Mixed Models
  • GWAS
  • Image Analysis
  • RNA-Seq
  • Spatial Point Processes

Special Interests

Dr. Vestal has expertise in the analysis of genetic and genomic data, quantitative image analysis with applications in computed tomography and emphysema, Bayesian hierarchical modeling, and computational statistics.

Using advanced statistical modeling, Dr. Vestal has created an AI image analysis technology to provide quantitative measurements of Emphysema in Computed Tomography scans. The Emphysema PROfiler™ technology has been supported by Microsoft to provide analysis for collaborators in a secure cloud environment. 


University of Colorado Denver, Denver, CO, PhD in Biostatistics
Californa State University Fullerton, Fullerton, CA, MA in Applied Mathematics
Vanguard University, Costa Mesa, CA, BS in Mathematics

Professional Memberships



Vestal BE, Carlson NE, Estépar RS, Fingerlin T, Ghosh D, Kechris K, Lynch D. Using a spatial point process framework to characterize lung computed tomography scans. Spatial Statistics. 2019 Mar 1;29:243-67.

Vestal B, Russell P, Radcliffe RA, Bemis L, Saba LM, Kechris K. miRNA-regulated transcription associated with mouse strains predisposed to hypnotic effects of ethanol. Brain Behav. 2018;e00989

Rudra P , Shi WJ, Vestal B, Russell PH, Odell A, Dowell RD, Radcliffe RA, Saba LM, Kechris K. Model based heritability scores for high-throughput sequencing data. BMC bioinformatics. 2017 Dec;18(1):143.

Rudra P, Shi WJ, Russell P, Vestal B, Tabakoff B, Hoffman P, Kechris K, Saba L. Predictive modeling of miRNA-mediated predisposition to alcohol-related phenotypes in mouse. BMC genomics. 2018 Dec;19(1):639.

Russell PH, Vestal B, Shi W, Rudra PD, Dowell R, Radcliffe R, Saba L, Kechris K. miR-MaGiC improves quantification accuracy for small RNA-seq. BMC research notes. 2018 Dec;11(1):296.

Academic Affiliations

Clinical Assistant Professor, Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Denver

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  • Office: 303.398.1464
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