Brian P. O'Connor, PhD Ask a Question Refer Patient Brian P. O'Connor, PhD, is a researcher at National Jewish Health. Dr. O'Connor is in the Division of Cell Biology and Department of Pediatrics. Associate Professor Office of Academic Affairs Center for Genes, Environment & Health Department of Pediatrics Division of Cell Biology 5280 Top Doctors 2022 Previously a 5280 Top Doctor America’s Top Doctors 2015 — Castle Connolly, Medical, Ltd. Recognized in America’s Top Doctors — Castle Connolly, Inc. Best Doctors in America® 2019-2020 — Best Doctors, Inc. Recognized in Best Doctors in America® — Best Doctors, Inc. America’s Top Doctors 2020 — Castle Connolly Medical, Ltd. Email Profile Print Profile Overview Contact Info & Locations Programs & Services Cell Biology Research Areas Epigenetics Genomics Histone Biology Immunobiology Allergy Special Interests Research Interests In recent years, epigenetic mechanisms, such as histone modification and DNA methylation, have been identified which, translate environmental signals into gene regulation. These molecular epigenetic processes, translate the myriad environmental signals encountered each day, into definitive regulation of our genome, and by extension, who we are at a basic biological level. Dr. O’Connor’s work focuses on understanding at a molecular and organismal level, how epigenetic mechanisms regulate the decision processes governing immune cell activity in the context of disease. The immune system is comprised of multiple types of autonomous cells that must work together to influence the outcome of disease. Currently, Dr. O’Connor’s lab examines the cross talk between environmental stimuli (such as diet or inflammation), the immune system, and disease (such as Asthma). See More View Publications Education Education 2003 Dartmouth College, Immunology, PhD Fellowship 2008 University of North Carolina at Chapel Hill, Postdoctoral Fellow Website Information O'Connor Laboratory Conflicts of Interest National Jewish Health physicians and scientists may collaborate with pharmaceutical or other industries to develop medical and scientific breakthroughs or to provide education on trends in quality medical practice and outcomes to physicians and health professionals around the country. National Jewish Health maintains a strict conflict of interest policy to ensure that all potential conflicts are clearly visible and that management plans are put in place in order to further innovation and education while ensuring the protection of our patients and the integrity of our research. National Jewish Health publicly discloses any payment to our physicians or scientists. View this faculty member’s industry relationships and collaborations. Ask a Question through Patient Portal Sign in to your My National Jewish Health patient portal account to communicate with your care team, manage appointments, and more. Create an Account Contact Information Office: 303.270.2754 Email: firstname.lastname@example.org Locations National Jewish Health Main Campus 1400 Jackson St. Denver, CO 80206 Patient Ratings The Patient Rating score is an average of all responses to care provider related questions on our independent rating system, the Press Ganey Patient Satisfaction Survey. This survey is about the patient care experience and does not address crucial characteristics like medical decision-making, prescribing the best therapy, and patient outcomes. Responses are measured on a scale of 1 to 5, with 5 being the best score. Learn more about our patient satisfaction survey. Comments Comments are collected in our Press Ganey Patient Satisfaction Surveys. Patients are de-identified to protect confidentiality and patient privacy. Learn more about our patient satisfaction survey.